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2,3-Dichloroacetophenone

2,3-Dichloroacetophenone Structure
  • ₹0
  • Product name: 2,3-Dichloroacetophenone
  • CAS: 56041-57-7
  • MF: C8H6Cl2O
  • MW: 189.04
  • EINECS:259-954-3
  • MDL Number:MFCD00052988
  • Synonyms:2,3-Dichloroacetophenone;1-(2,3-DICHLOROPHENYL)ETHAN-1-ONE;Ethanone,1-(2,3-dichlorophenyl)-;2',3'-Dichloroacetophenone;1-(2,3-Dichlorophenyl)ethanone;Ketoconazole Impurity 47;2',3'-Dichloroacetophenone
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :125-127 °C
Boiling point :67 °C
Density :1.293
refractive index :1.558
Flash point :106-108°C/2mm
storage temp. :Sealed in dry,Room Temperature
solubility :Chloroform (Slightly), Ethyl Acetate (Slightly)
form :Solid
color :Colourless
BRN :2438815
CAS DataBase Reference :56041-57-7(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.

Description

2,3''-Dichloroacetophenone is used as a reagent in the synthesis of benzothiazepinones (BTZs) as novel non-ATP competitive inhibitors of glycogen synthase kinase-3β (GSK-3β). Also used as a reagent in the synthesis of benzimidazolyl pyridinones as insulin-like growth factor I (IGF-1R) kinase inhibitors.

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