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ChemicalBook > Product Catalogue >Analytical Chemistry >Standard >Pharmaceutical Impurity Reference Standards >Δ2-Cefuroxime Axetil

Δ2-Cefuroxime Axetil

Δ2-Cefuroxime Axetil Structure
  • ₹0
  • Product name: Δ2-Cefuroxime Axetil
  • CAS: 123458-61-7
  • MF: C20H22N4O10S
  • MW: 510.47
  • EINECS:
  • MDL Number:MFCD00864991
  • Synonyms:Δ2-Cefuroxime Axetil;(6R,7R)-3-[[(AMinocarbonyl)oxy]Methyl]-7-[[(2Z)-2-(2-furanyl)-2-(MethoxyiMino)acetyl]aMino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-3-ene-2-carboxylic Acid 1-(Acetyloxy)ethyl Ester;[6R-[6α, 7β(Z)]]-3-[[(Aminocarbonyl)oxy]methyl]-7-[[2-furanyl(methoxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-3-ene-2-carboxylic acid 1-(acetyloxy)ethyl ester;Cefuroxim axetil impurity A;Cefuroxim Impurity 34;5-Thia-1-azabicyclo[4.2.0]oct-3-ene-2-carboxylic acid, 3-[[(aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-(2-furanyl)-2-(methoxyimino)acetyl]amino]-8-oxo-, 1-(acetyloxy)ethyl ester, (6R,7R)-;Δ2-Cefuroxime Axetil (Cefuroxime Axetil Delta-3 Isomer);1-acetyloxyethyl (6R,7R)-3-(carbamoyloxymethyl)-7-[[(2Z)-2-(furan-2-yl)-2-methoxyiminoacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-3-ene-2-carboxylate
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Properties

Melting point :64-71°C
Density :1.61±0.1 g/cm3(Predicted)
storage temp. :Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility :DMSO (Slightly), Methanol (Slightly)
pka :8.33±0.60(Predicted)
color :White to Pale Yellow
Stability :Hygroscopic

Safety Information

Symbol(GHS):
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Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
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Description

Δ2-Cefuroxime Axetil (Cefuroxime Axetil EP Impurity A) is an oral prodrug of Cefuroxime (C248060), an injectable second generation cephalosporin with an excellent antibacterial activity. This ester is applied in therapy as a mixture of the R and S diastereoisomers.