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ChemicalBook > Product Catalogue >Analytical Chemistry >Standard >Pharmaceutical Impurity Reference Standards >2-Pyrrolidinone

2-Pyrrolidinone

2-Pyrrolidinone Structure
  • ₹890 - ₹87630
  • Product name: 2-Pyrrolidinone
  • CAS: 616-45-5
  • MF: C4H7NO
  • MW: 85.1
  • EINECS:210-483-1
  • MDL Number:MFCD00005270
  • Synonyms:-Tetrahydropyrrolone;zacyclopentan-2-one;α-PVR ;Piperidinic acid anhydride;gama-Butyrolactam;2-PYRROLIDINONE, 99+%;2-Pyrrolidinone,Certified;2-Pyrrolidone,>98%
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  • Sigma-Aldrich(India)
  • ALFA India
  • TCI Chemicals (India)
  • SRL
  • ottokemi

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  • ManufacturerSigma-Aldrich(India)
  • Product numberP74370
  • Product description2-Pyrrolidinone 99%
  • Packaging25G
  • Price₹984
  • Updated2022-06-14
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  • ManufacturerSigma-Aldrich(India)
  • Product numberP74370
  • Product description2-Pyrrolidinone 99%
  • Packaging500G
  • Price₹2013.45
  • Updated2022-06-14
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  • ManufacturerSigma-Aldrich(India)
  • Product number83300
  • Product description2-Pyrrolidinone purum, ≥98.0% (GC)
  • Packaging250ML
  • Price₹2652.13
  • Updated2022-06-14
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  • ManufacturerSigma-Aldrich(India)
  • Product numberP74370
  • Product description2-Pyrrolidinone 99%
  • Packaging1KG
  • Price₹3615.55
  • Updated2022-06-14
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  • ManufacturerSigma-Aldrich(India)
  • Product number8.07041
  • Product description2-Pyrrolidone for synthesis
  • Packaging5ML
  • Price₹4890
  • Updated2022-06-14
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  • ManufacturerSigma-Aldrich(India)
  • Product number8.07041
  • Product description2-Pyrrolidone for synthesis
  • Packaging250ML
  • Price₹6150
  • Updated2022-06-14
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  • ManufacturerSigma-Aldrich(India)
  • Product number8.07041
  • Product description2-Pyrrolidone for synthesis
  • Packaging25KG
  • Price₹87630
  • Updated2022-06-14
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  • ManufacturerSigma-Aldrich(India)
  • Product number83300
  • Product description2-Pyrrolidinone purum, ≥98.0% (GC)
  • Packaging1L
  • Price₹6484.18
  • Updated2022-06-14
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  • ManufacturerSigma-Aldrich(India)
  • Product number240338
  • Product description2-Pyrrolidinone ≥99%
  • Packaging50G
  • Price₹7252.75
  • Updated2022-06-14
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  • ManufacturerSigma-Aldrich(India)
  • Product numberW482900
  • Product description2-Pyrrolidinone 99%
  • Packaging100G
  • Price₹10121.38
  • Updated2022-06-14
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  • ManufacturerSigma-Aldrich(India)
  • Product number8.07041
  • Product description2-Pyrrolidone for synthesis
  • Packaging1L
  • Price₹11380
  • Updated2022-06-14
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  • ManufacturerSigma-Aldrich(India)
  • Product numberW482900
  • Product description2-Pyrrolidinone 99%
  • Packaging500G
  • Price₹38028.23
  • Updated2022-06-14
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  • ManufacturerSigma-Aldrich(India)
  • Product numberP74370
  • Product description2-Pyrrolidinone 99%
  • Packaging18KG
  • Price₹75417.78
  • Updated2022-06-14
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  • ManufacturerALFA India
  • Product numberALF-A15332-A3
  • Product description2-Pyrrolidinone, 99%
  • Packaging2kg
  • Price₹11197
  • Updated2022-05-26
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  • ManufacturerALFA India
  • Product numberALF-A15332-36
  • Product description2-Pyrrolidinone, 99%
  • Packaging500g
  • Price₹3516
  • Updated2022-05-26
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  • ManufacturerTCI Chemicals (India)
  • Product numberP0575
  • Product description2-Pyrrolidone min. 98.0 %
  • Packaging25G
  • Price₹1500
  • Updated2022-05-26
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Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) P74370 2-Pyrrolidinone 99% 25G ₹984 2022-06-14 Buy
Sigma-Aldrich(India) P74370 2-Pyrrolidinone 99% 500G ₹2013.45 2022-06-14 Buy
Sigma-Aldrich(India) 83300 2-Pyrrolidinone purum, ≥98.0% (GC) 250ML ₹2652.13 2022-06-14 Buy
Sigma-Aldrich(India) P74370 2-Pyrrolidinone 99% 1KG ₹3615.55 2022-06-14 Buy
Sigma-Aldrich(India) 8.07041 2-Pyrrolidone for synthesis 5ML ₹4890 2022-06-14 Buy
Sigma-Aldrich(India) 8.07041 2-Pyrrolidone for synthesis 250ML ₹6150 2022-06-14 Buy
Sigma-Aldrich(India) 8.07041 2-Pyrrolidone for synthesis 25KG ₹87630 2022-06-14 Buy
Sigma-Aldrich(India) 83300 2-Pyrrolidinone purum, ≥98.0% (GC) 1L ₹6484.18 2022-06-14 Buy
Sigma-Aldrich(India) 240338 2-Pyrrolidinone ≥99% 50G ₹7252.75 2022-06-14 Buy
Sigma-Aldrich(India) W482900 2-Pyrrolidinone 99% 100G ₹10121.38 2022-06-14 Buy
Sigma-Aldrich(India) 8.07041 2-Pyrrolidone for synthesis 1L ₹11380 2022-06-14 Buy
Sigma-Aldrich(India) W482900 2-Pyrrolidinone 99% 500G ₹38028.23 2022-06-14 Buy
Sigma-Aldrich(India) P74370 2-Pyrrolidinone 99% 18KG ₹75417.78 2022-06-14 Buy
ALFA India ALF-A15332-A3 2-Pyrrolidinone, 99% 2kg ₹11197 2022-05-26 Buy
ALFA India ALF-A15332-36 2-Pyrrolidinone, 99% 500g ₹3516 2022-05-26 Buy
TCI Chemicals (India) P0575 2-Pyrrolidone min. 98.0 % 25G ₹1500 2022-05-26 Buy

Properties

Melting point :23-25 °C (lit.)
Boiling point :245 °C (lit.)
Density :1.12 g/mL at 25 °C (lit.)
vapor density :2.9 (vs air)
vapor pressure :0.04 hPa (20 °C)
refractive index :n20/D 1.487(lit.)
FEMA :4829 | 2-PYRROLIDONE
Flash point :>230 °F
storage temp. :2-8°C
solubility :H2O: miscible (completely)
pka :16.62±0.20(Predicted)
form :Liquid
color :Clear colorless to pale yellow
PH :9-11 (100g/l, H2O, 20℃)
explosive limit :1.8-16.6%(V)
Water Solubility :miscible
Sensitive :Hygroscopic
Merck :14,8016
BRN :105241
Stability :Hygroscopic
InChIKey :HNJBEVLQSNELDL-UHFFFAOYSA-N
LogP :-0.71 at 20℃
CAS DataBase Reference :616-45-5(CAS DataBase Reference)
NIST Chemistry Reference :2-Pyrrolidinone(616-45-5)
EPA Substance Registry System :2-Pyrrolidinone (616-45-5)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

2-pyrrolidone carboxylic acid, also known as pyroglutamic acid, is a derivative of the glutamine and glutamate. It is contained in many kinds of proteins including bacteriorhodopsin. It is a nonessential nutrient which can be normally generated during the glutathione cycle process inside the human body. It is also contained in fruits and vegetables. Pyroglutamic acid has many physiological functions and healthy effects. Its L-form can increase the activity off neurotransmitter acetylcholine and can be used in the production of the neurotransmitters gramma-aminobutyric acid (GABA) as well as glycine. Based on this, L-pyroglutamic acid is beneficial to brain function, being capable of supporting memory and learning as well as alleviating anxiety. In addition, its sodium-form product (sodium pyroglutamate), as a humectant, can be used for dry skin and hair products.

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