RILMENIDINE HEMIFUMARATE SALT
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- ₹11831.73 - ₹51494.53
- Product name: RILMENIDINE HEMIFUMARATE SALT
- CAS: 207572-68-7
- MF: 2C10H16N2O.C4H4O4
- MW: 476.57
- EINECS:
- MDL Number:MFCD09878261
- Synonyms:RILMENIDINE HEMIFUMARATE SALT;n-(dicyclopropylmethyl)-4,5-dihydro-2-oxazolamine hemifumarate salt;Oxaminozoline hemifumarate salt, Rilmenidene hemifumarate salt, N-(Dicyclopropylmethyl)-4,5-dihydro-2-oxazolamine hemifumarate salt;LZFATBMLSYHRTC-WXXKFALUSA-N
2 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 5MG
- 25MG
- ManufacturerSigma-Aldrich(India)
- Product numberR134
- Product descriptionRilmenidine hemifumarate salt solid
- Packaging5MG
- Price₹11831.73
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product numberR134
- Product descriptionRilmenidine hemifumarate salt solid
- Packaging25MG
- Price₹51494.53
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | R134 | Rilmenidine hemifumarate salt solid | 5MG | ₹11831.73 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | R134 | Rilmenidine hemifumarate salt solid | 25MG | ₹51494.53 | 2022-06-14 | Buy |
Properties
storage temp. :Store at -20°C
solubility :DMSO: >10mg/mL
form :solid
color :white
solubility :DMSO: >10mg/mL
form :solid
color :white
Safety Information
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Description
Rilmenidine is a centrally acting antihypertensive agent that has been shown to lower arterial pressure in various animal models by inhibiting the tonic activity of sympathoexcitatory neurons in the rostral ventrolateral medulla. Rilmenidine targets the nonadrenergic imidazoline-binding site I1 receptor with a Ki value of 7.1 nM and demonstrates weaker affinity for the I2 receptor with a Ki value of 5.2 μM. It can also act as an agonist of α2-adrenergic receptors, but demonstrates ~30-fold greater selectivity for I1 receptors compared to α2-adrenergic receptors. Rilmenidine is reported to induce autophagy as evidenced by a ~350% increase in LC3-II levels in PC12 cells when treated with 1 μM of the I1 agonist.Suppliers and manufacturers
CLEARSYNTH LABS LTD.
Hangzhou MolCore BioPharmatech Co.,Ltd.
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd
Aladdin Scientific
ShangHai ChuanQian Chemcial Technique Centre
Shanghai Aladdin Biochemical Technology Co.,Ltd.
TargetMol Chemicals Inc.
Jiangsu Aikon Biopharmaceutical R&D Co.,Ltd.
BOC Sciences
ShangHai Caerulum Pharma Discovery Co., Ltd.