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ChemicalBook > Product Catalogue >Analytical Chemistry >Standard >Pharmaceutical Impurity Reference Standards >IMp. E (EP): 1,4-Bis(diphenylMethyl)piperazine

IMp. E (EP): 1,4-Bis(diphenylMethyl)piperazine

IMp. E (EP): 1,4-Bis(diphenylMethyl)piperazine Structure
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  • Product name: IMp. E (EP): 1,4-Bis(diphenylMethyl)piperazine
  • CAS: 216581-01-0
  • MF: C30H30N2
  • MW: 418.57
  • EINECS:
  • MDL Number:MFCD00225204
  • Synonyms:IMp. E (EP): 1,4-Bis(diphenylMethyl)piperazine;Cinnarizine EP IMpurity E;Cinnarizine IMpurity E;1,4-Dibenzhydrylpiperazine dihydrochloride;1,4-bis-(Diphenylmethyl)piperazine;Cinnarizine Impurity 5(Cinnarizine EP Impurity E);1,4-Bis(benzhydryl)piperazine;Piperazine, 1,4-bis(diphenylmethyl)-
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Properties

Melting point :>235°C (dec.)
Boiling point :526.2±45.0 °C(Predicted)
Density :1.122±0.06 g/cm3(Predicted)
storage temp. :Amber Vial, Refrigerator, Under inert atmosphere
solubility :Chloroform (Slightly), DMSO (Slightly, Heated)
form :Solid
pka :6.17±0.10(Predicted)
color :White to Off-White
Stability :Light Sensitive

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

1,4-Bis(benzhydryl)piperazine is a cinnarizine (C465300) impurity. Cinnarizine is an anti-vasoconstricting agent (1), as well as a calcium channel blocker (2,3) with antiallergic activity. Antihistaminic.

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