4-AMINO-1-TERT-BUTYL-3-(1'-NAPHTHYL)PYRAZOLO[3,4-D]PYRIMIDINE
![4-AMINO-1-TERT-BUTYL-3-(1'-NAPHTHYL)PYRAZOLO[3,4-D]PYRIMIDINE Structure](/CAS/GIF/221243-82-9.gif)
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- Product name: 4-AMINO-1-TERT-BUTYL-3-(1'-NAPHTHYL)PYRAZOLO[3,4-D]PYRIMIDINE
- CAS: 221243-82-9
- MF: C19H19N5
- MW: 317.39
- EINECS:
- MDL Number:MFCD03425471
- Synonyms:4-AMINO-1-TERT-BUTYL-3-(1'-NAPHTHYL)PYRAZOLO[3,4-D]PYRIMIDINE;1-NA-PP1;1-tert-butyl-3-(naphthalen-1-yl)-1H-pyrazolo[3,4-d]pyriMidin-4-aMine;1-(1,1-Dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine;1-Naphthyl PP1;1-NAPHTHYL PP1(1-NA-PP 1);CS-2001;1H-Pyrazolo[3,4-d]pyrimidin-4-amine,1-(1,1-dimethylethyl)-3-(1-naphthalenyl)-
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Properties
Melting point :219-222°C
storage temp. :Keep in dark place,Inert atmosphere,2-8°C
solubility :Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form :Solid
color :White to Off-White
storage temp. :Keep in dark place,Inert atmosphere,2-8°C
solubility :Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form :Solid
color :White to Off-White
Safety Information
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Description
1-NA-PP1 is a reversible, cell-permeable inhibitor of Src-family tyrosine kinases that have been mutated, by a single base substitution, to become ‘analog sensitive’ (as), as compared to the wild-type kinase. 1-NA-PP1 was first developed to optimally inhibit v-Src-as1, with an I338G substitution, preferentially over v-Src (IC50 = 1.5 nM versus 1.0 μM, respectively). The homologous mutation in other kinases generated similar analog sensitivity (e.g., IC50 = 1.5 nM for c-Fyn-as1 versus 0.6 μM for c-Fyn; 7.0 nM for c-Abl-as2 versus 0.6 μM for c-Abl; 15 nM for Cdk2-as1 versus 18 μM for Cdk2). This approach has been used to elucidate functions of several kinases in both mammalian and yeast systems.Related product price
- 1 NM-PP1
₹10310-15469.99 - PP1
₹21390.2-86112.88 - 2,6-Di-tert-butylphenol
₹891-13899.3
Suppliers and manufacturers
career henan chemical co
![4-AMINO-1-TERT-BUTYL-3-(1'-NAPHTHYL)PYRAZOLO[3,4-D]PYRIMIDINE](https://img.chemicalbook.com/ProductImageEN/2020-1/small/9dd44a88-4324-4f38-8353-d4de078758bb.png)
ATK CHEMICAL COMPANY LIMITED
BOC Sciences
Finetech Industry Limited
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
Coresyn Pharmatech Co., Ltd.
TargetMol Chemicals Inc.
ShenZhen Trendseen Biological Technology Co.,Ltd.
LEAPCHEM CO., LTD.
₹9.80 /1.79999995231628KG
4-AMINO-1-TERT-BUTYL-3-(1'-NAPHTHYL)PYRAZOLO[3,4-D]PYRIMIDINE CAS:221243-82-9
4-AMINO-1-TERT-BUTYL-3-(1'-NAPHTHYL)PYRAZOLO[3,4-D]PYRIMIDINE CAS:221243-82-9