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3-Azabicyclo[3.1.0]hexane-3-carboxylicacid,6-amino-,1,1-dimethylethylester,

3-Azabicyclo[3.1.0]hexane-3-carboxylicacid,6-amino-,1,1-dimethylethylester, Structure
  • ₹0
  • Product name: 3-Azabicyclo[3.1.0]hexane-3-carboxylicacid,6-amino-,1,1-dimethylethylester,
  • CAS: 273206-92-1
  • MF: C10H18N2O2
  • MW: 198.27
  • EINECS:
  • MDL Number:MFCD09832898
  • Synonyms:tert-Butyl rel-(1R,5S,6S)-6-amino-3-azabicyclo[3.1.0]hexane-3-carboxylate;(1α,5α,6α)-6-AMino-3-azabicyclo[3.1.0]hexane-3-carboxylic Acid 1,1-DiMethylethyl Ester;exo-6-Amino-3-aza-bicyclo[3.1.0]hexane-3-carboxylic acid tert-butyl ester;3-Azabicyclo[3.1.0]hexane-3-carboxylic acid, 6-amino-, 1,1-dimethylethyl ester, (1alpha,5alpha,6alpha)-;tert-butyl (1S,5R)-6-amino-3-azabicyclo[3.1.0]hexane-3-carboxylate;tert-butyl (exo-6-amino-3-azabicyclo[3.1.0]hexane-3-carboxylate;trans-tert-butyl 6-amino-3-azabicyclo[3.1.0]hexane-3-carboxylate;exo-6-Amino-3-Boc-3-azabicyclo[3.1.0]hexane
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Boiling point :275℃
Density :1.144
Flash point :120℃
storage temp. :under inert gas (nitrogen or Argon) at 2–8 °C
pka :8.52±0.20(Predicted)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H312 Harmful in contact with skin Acute toxicity,dermal Category 4 Warning GHS hazard pictograms P280,P302+P352, P312, P322, P363,P501
H332 Harmful if inhaled Acute toxicity,inhalation Category 4 Warning GHS hazard pictograms P261, P271, P304+P340, P312
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P330 Rinse mouth.
P363 Wash contaminated clothing before reuse.
P501 Dispose of contents/container to..…

Description

(1α,5α,6α)-6-Amino-3-azabicyclo[3.1.0]hexane-3-carboxylic Acid 1,1-Dimethylethyl Ester, is an intermediate in the preparation of a novel series of Histone Deacetylase (HDAC) Inhibitors, demonstrating class I selectivity and good oral bioavailability. It can also be used in the synthesis of Alatrofloxacin Mesylate (A511400).

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