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ChemicalBook > Product Catalogue >Pharmaceutical intermediates >Bulk Drug Intermediates >2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one

2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one

2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one Structure
  • ₹6700 - ₹16500
  • Product name: 2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one
  • CAS: 277299-70-4
  • MF: C12H14N2O
  • MW: 202.25
  • EINECS:1592732-453-0
  • MDL Number:MFCD09795980
  • Synonyms:2-(3,4-dimethylphenyl)-5-methyl-1H-pyrazol-3-one;2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one;2-(3,4-Dimethylphenyl)-5-methyl-1H-pyrazol-3(2H)-one;Eltrombopag Intermediate 1;EltroMbopag II;2-Oxo-2,4,5,6,7,7a-Hexahydrothieno [3,2-c] Pyridine;1-(3,4-diMethylphenyl)-3-Methyl-1H-pyrazol-5-ol;1H-pyrazol-3(2H)-one,2-(3,4-Dimethylphenyl)-5-methyl-
2 prices
Selected condition:

Brand

  • TCI Chemicals (India)

Package

  • 1G
  • 5G
  • ManufacturerTCI Chemicals (India)
  • Product numberD5064
  • Product description1-(3,4-Dimethylphenyl)-3-methyl-5-pyrazolone min. 97.0 %
  • Packaging1G
  • Price₹6700
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberD5064
  • Product description1-(3,4-Dimethylphenyl)-3-methyl-5-pyrazolone min. 97.0 %
  • Packaging5G
  • Price₹16500
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) D5064 1-(3,4-Dimethylphenyl)-3-methyl-5-pyrazolone min. 97.0 % 1G ₹6700 2022-05-26 Buy
TCI Chemicals (India) D5064 1-(3,4-Dimethylphenyl)-3-methyl-5-pyrazolone min. 97.0 % 5G ₹16500 2022-05-26 Buy

Properties

Melting point :121.0 to 125.0 °C
Boiling point :338.5±52.0 °C(Predicted)
Density :1.121
storage temp. :Sealed in dry,Room Temperature
solubility :Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form :Solid
pka :0.79±0.40(Predicted)
color :Pale Beige to Light Beige

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.
P501 Dispose of contents/container to..…

Description

2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one, is an impurity of Eltrombopag (E508000), which is agonist of the Thrombopoietin (Tpo) receptor, used as treatment for thrombocytopenia.

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