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(2R,4R)-APDC

(2R,4R)-APDC Structure
  • ₹0
  • Product name: (2R,4R)-APDC
  • CAS: 169209-63-6
  • MF: C6H10N2O4
  • MW: 174.15
  • EINECS:
  • MDL Number:MFCD00672677
  • Synonyms:LY-314,593;2,4-Pyrrolidinedicarboxylicacid,4-amino-,(2R,4R)-(9CI);(2R,4R)-APDC;(2R,4R)-4-AMINOPYRROLIDINE-2,4-DICARBOXYLATE;(2R,4R)-4-AMINOPYRROLIDINE-2,4-DICARBOXYLIC ACID;2R, 4R-APDC monohydrate;4-amino-2,4-pyrrolidinedicarboxylic acid;2,4-Pyrrolidinedicarboxylic acid, 4-amino-, (2R,4R)-
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

storage temp. :Desiccate at RT
solubility :H2O: ≥2mg/mL
form :powder
color :white
Water Solubility :Soluble to 100 mM in water

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

(2R,4R)-APDC is a highly potent and highly selective agonist for mGluR-2 (group II metabotropic glutamate receptors). The compound is useful for investigating the functions of metabotropic glutamate receptors in situ. (2R,4R)-APDC inhibits the NADPH-oxidase dependent ROS system. (2R,4R)-APDC is an activator of mGluR-3.

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