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ChemicalBook > Product Catalogue >Chemical Reagents >Organic reagents >fatty acid >3-NITROPROPIONIC ACID

3-NITROPROPIONIC ACID

3-NITROPROPIONIC ACID Structure
  • ₹8310 - ₹55478.13
  • Product name: 3-NITROPROPIONIC ACID
  • CAS: 504-88-1
  • MF: C3H5NO4
  • MW: 119.08
  • EINECS:208-003-0
  • MDL Number:MFCD00007406
  • Synonyms:BETA-NITROPROPANOICACID;3-Nitropropionic acid,99%;3-nitropropanoate;3-3-Nitropropionic Acid;Nitro-propanoic acid;NSC 64266;BETA-NITROPROPIONIC ACID;3-nitropropanoicacid
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Brand

  • Sigma-Aldrich(India)

Package

  • 50MG
  • 1G
  • 10G
  • ManufacturerSigma-Aldrich(India)
  • Product number164603
  • Product description3-Nitropropionic acid - CAS 504-88-1 - Calbiochem A cell-permeable, irreversible inactivator (~3 mM) of succinate dehydrogenase that upon oxidation by Complex II forms a covalent adduct with Arg297 in
  • Packaging50MG
  • Price₹8310
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberN5636
  • Product description3-Nitropropionic acid ≥97%
  • Packaging1G
  • Price₹8670.83
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberN22908
  • Product description3-Nitropropionic acid 97%
  • Packaging10G
  • Price₹17774.65
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberN5636
  • Product description3-Nitropropionic acid ≥97%
  • Packaging10G
  • Price₹55478.13
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 164603 3-Nitropropionic acid - CAS 504-88-1 - Calbiochem A cell-permeable, irreversible inactivator (~3 mM) of succinate dehydrogenase that upon oxidation by Complex II forms a covalent adduct with Arg297 in 50MG ₹8310 2022-06-14 Buy
Sigma-Aldrich(India) N5636 3-Nitropropionic acid ≥97% 1G ₹8670.83 2022-06-14 Buy
Sigma-Aldrich(India) N22908 3-Nitropropionic acid 97% 10G ₹17774.65 2022-06-14 Buy
Sigma-Aldrich(India) N5636 3-Nitropropionic acid ≥97% 10G ₹55478.13 2022-06-14 Buy

Properties

Melting point :68-70 °C (lit.)
Boiling point :222.3°C (rough estimate)
Density :1.6731 (rough estimate)
refractive index :1.4940 (estimate)
storage temp. :2-8°C
solubility :alcohol: 100 mg/mL, may be light yellow
form :powder or crystals
pka :3.66±0.10(Predicted)
color :white to light yellow
BRN :1759889
Stability :Stable. Incompatible with strong oxidizing agents, bases, reducing agents.
EPA Substance Registry System :3-Nitropropanoic acid (504-88-1)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
Precautionary statements:

Description

3-Nitropropionic acid (3-NP) is an irreversible inhibitor of mitochondrial respiratory Complex II succinate dehydrogenase, resulting in energy depletion through disruption of the electron transport chain. This compound is a natural toxin of certain plants and fungi. Administration of 3-NP to rats (12 mg/kg per day) produces progressive striatal degeneration, while lower doses (8 mg/kg daily) in nonhuman primates results in neuropathologic and clinical features of Huntington’s disease. Conversely, Huntington’s disease results in a loss of Complex II activity. 3-NP also induces convulsions and is used to examine interventions effective in a mouse model of epilepsy.

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