15(R)-15-METHYL PROSTAGLANDIN F2ALPHA
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- Product name: 15(R)-15-METHYL PROSTAGLANDIN F2ALPHA
- CAS: 35864-81-4
- MF: C21H36O5
- MW: 368.51
- EINECS:
- MDL Number:MFCD00135246
- Synonyms:15(R)-Methyl prostaglandin F2alpha;15(R)-15-METHYL PROSTAGLANDIN F2ALPHA;9ALPHA,11ALPHA,15R-TRIHYDROXY-15-METHYL-PROSTA-5Z,13E-DIEN-1-OIC ACID;15(R)-Carboprost;(5Z,9α,11α,13E,15R)-9,11,15-Trihydroxy-15-methyl-prosta-5,13-dien-1-oic Acid;15(R)-Methylprostaglandin F2α;ONO 373;Carboprost Trometamol EP Impurity B:Carboprost Trometamol Impurity B
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Properties
Boiling point :536.6±50.0 °C(Predicted)
Density :1.139±0.06 g/cm3(Predicted)
solubility :10 mM Na2CO3: >6.5 mg/ml; DMF: >100 mg/ml; DMSO: >100 mg/ml; Ethanol: >100 mg/ml; PBS pH 7.2: >10 mg/ml
pka :4.76±0.10(Predicted)
Density :1.139±0.06 g/cm3(Predicted)
solubility :10 mM Na2CO3: >6.5 mg/ml; DMF: >100 mg/ml; DMSO: >100 mg/ml; Ethanol: >100 mg/ml; PBS pH 7.2: >10 mg/ml
pka :4.76±0.10(Predicted)
Safety Information
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Description
15(R)-15-methyl PGF2α is a metabolically stable analog of PGF2α. 15(R)-15-methyl PGF2α is an inactive, prodrug PGF agonist designed for activation by gastric acid after oral administration. Acid-catalyzed epimerization of 15(R)-15-methyl PGF2α converts it into the active 15(S)-isomer. The 15(S)-isomer induces luteolysis when injected in rhesus monkeys at a dose of about 12 mg/animal, while the 15(R)-isomer does not.Suppliers and manufacturers
CHEMAZON LABORATORIES
CLEARSYNTH LABS LTD.
Pharmaffiliates Analytics and Synthetics P. Ltd
Pharma Affiliates
China National Standard Pharmaceutical Corporation Limited
Cayman Chemical Company
Shanghai Yifei Biotechnology Co. , Ltd.
Shanghai Zerui Biotechnology Co., Ltd.
Hubei Moco Chemical Co., Ltd.
TOSUN PHARM