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ChemicalBook > Product Catalogue >Organic Chemistry >Organic fluorine compound >Fluoro phenylacetic series >α,α-Difluorophenylacetic acid

α,α-Difluorophenylacetic acid

α,α-Difluorophenylacetic acid Structure
  • ₹0
  • Product name: α,α-Difluorophenylacetic acid
  • CAS: 360-03-2
  • MF: C8H6F2O2
  • MW: 172.13
  • EINECS:623-610-4
  • MDL Number:MFCD00498146
  • Synonyms:DIFLUORO(PHENYL)ACETIC ACID;2,2-DIFLUORO-2-PHENYLACETIC ACID;A,A-DIFLUOROPHENYLACETIC ACID;ALPHA,ALPHA-DIFLUOROPHENYLACETIC ACID;alpha-Difluoro-benzeneacetic acid;ɑ,ɑ-Difluorophenylacetic acid, 99%;2,3-DIFLUOROPHENYLACETIC ACID 95+%;2,3-DIFLUUOROPHENYL ACETIC ACID
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :65-75 °C
Boiling point :0°C
Density :1.338±0.06 g/cm3(Predicted)
Flash point :0°C
storage temp. :Refrigerator, Under inert atmosphere
solubility :Chloroform (Sparingly), DMSO (Sparingly), Methanol (Slightly)
form :Solid
pka :1.04±0.10(Predicted)
color :White to Pale Yellow
CAS DataBase Reference :360-03-2(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

α,α-Difluorophenylacetic acid is a phenylacetic acid with two fluorides on the benzylic carbon. The inductive effect of the difluoromethyl group increases the acidity of α,α-difluorophenylacetic acid. α,α-difluorophenylacetic acid and 2-arylbenzoimidazoles could be used as reaction substrates to synthesise difluoroarymethyl-substituted benzimidazo[2,1-a]isoquinolin-6(5H)-ones through radical cascade cyclization[1].

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