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ChemicalBook > Product Catalogue >Organic Chemistry >Organic fluorine compound >Fluoro-benzoic acid series >2-Amino-6-fluorobenzoic acid

2-Amino-6-fluorobenzoic acid

2-Amino-6-fluorobenzoic acid Structure
  • ₹2400 - ₹6900
  • Product name: 2-Amino-6-fluorobenzoic acid
  • CAS: 434-76-4
  • MF: C7H6FNO2
  • MW: 155.13
  • EINECS:627-707-2
  • MDL Number:MFCD00067781
  • Synonyms:BUTTPARK 44\01-59;6-FLUOROANTHRANILIC ACID;2-fluoro-6-aminobenzoic acid;TRIPHENYLBORANE, 0.25M SOLUTION IN TETRA;2-AMINO-6-FLUOROBENZOIC ACID (6-FLUOROANTHRANILIC ACID);2-Amino-6-fluorobenzoic acid, 98% (6-Fluoroanthranilic acid);2-Amino-6-Fluorobenzoic;2-Amino-6-fluorobenzoic acid 97%
Price3 Properties Safety Information Description
3 prices
Selected condition：

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 1G
  • 5G
  • ManufacturerTCI Chemicals (India)
  • Product numberF0475
  • Product description2-Amino-6-fluorobenzoic Acid
  • Packaging1G
  • Price₹2400
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberF0475
  • Product description2-Amino-6-fluorobenzoic Acid
  • Packaging5G
  • Price₹6900
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number443026
  • Product description2-Amino-6-fluorobenzoic acid 98%
  • Packaging5G
  • Price₹5964.58
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) F0475 2-Amino-6-fluorobenzoic Acid 1G ₹2400 2022-05-26 Buy
TCI Chemicals (India) F0475 2-Amino-6-fluorobenzoic Acid 5G ₹6900 2022-05-26 Buy
Sigma-Aldrich(India) 443026 2-Amino-6-fluorobenzoic acid 98% 5G ₹5964.58 2022-06-14 Buy

Properties

Melting point :167-169 °C (lit.)
Boiling point :223.67°C (rough estimate)
Density :1.3021 (estimate)
storage temp. :Keep in dark place,Inert atmosphere,Room temperature
solubility :soluble in Methanol
pka :4.01±0.10(Predicted)
form :Crystalline Powder
color :Yellow to brown
BRN :3540926
InChIKey :RWSFZKWMVWPDGZ-UHFFFAOYSA-N
CAS DataBase Reference :434-76-4(CAS DataBase Reference)
NIST Chemistry Reference :Anthralic acid, 6-fluoro-(434-76-4)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Used in the synthesis of a novel benzamide with potent neuroleptic activity. 5- fluoro-2-methyl-3,l-benzoxazin-4-one was obtained from 2-amino-6-fluorobenzoic acid. The condensation of 2-amino-6-fluorobenzoic acid methyl ester and (4-fluorophenyl) acetyl chloride with N,N-dimethylamino-4-pyridine in CH 2 Cl 2 to give 2-fluoro-6-[2-(4-fluoro-phenyl)-acetylamino]-benzoic acid methyl ester in 61% yield. 2 Amino 6 fluorobenzoic acid is another easily ac cessible synthon for construction of monofluorinated heterocycles. Reactions of 2,3,4,6-tetra-O-acetyl-n-D_glucopyranosyl bromide (2) with p-hydroxybenzaldehyde, trifluoromethyl and fluoro substi- tuted aniline and 2-amino-6-fluorobenzoic acid gave lO-(Pformyl- pheny1)-2,3,4,6-tetra-O-acetyl-(3-D-glucopyranoside. 2-Fluoro-6-iodobenzoic acid,a loose white crystal,was synthesized by using 2-amino-6-fluorobenzoic acid as the starting material.

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