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ChemicalBook > Product Catalogue >Chemical Reagents >Organic reagents >Aromatic ketones >5-Hydroxy-1,4-naphthalenedione

5-Hydroxy-1,4-naphthalenedione

5-Hydroxy-1,4-naphthalenedione Structure
  • ₹2699 - ₹17341.65
  • Product name: 5-Hydroxy-1,4-naphthalenedione
  • CAS: 481-39-0
  • MF: C10H6O3
  • MW: 174.15
  • EINECS:207-567-5
  • MDL Number:MFCD00001684
  • Synonyms:5-Hydroxy-p-naphthoquinone, 97% 5GR;Juglone(NSC 34266;NSC 622948);5-Hydroxy-1,4-naphthoquinone 97%;RARECHEM BW GC 0025;WALNUT EXTRACT, WATER SOLUBLE;1,4-Naphthalenedione,5-hydroxy- ;1,4-Naphthoquinone, 5-hydroxy-
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Brand

  • ALFA India
  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 250MG
  • 1g
  • 5g
  • ManufacturerALFA India
  • Product numberALF-H28343-03
  • Product description5-Hydroxy-1,4-naphthoquinone, 99%
  • Packaging1g
  • Price₹2699
  • Updated2022-05-26
  • Buy
  • ManufacturerALFA India
  • Product numberALF-H28343-06
  • Product description5-Hydroxy-1,4-naphthoquinone, 99%
  • Packaging5g
  • Price₹13363
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberH0286
  • Product description5-Hydroxy-1,4-naphthoquinone min. 96.0 %
  • Packaging1G
  • Price₹3700
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberH0286
  • Product description5-Hydroxy-1,4-naphthoquinone min. 96.0 %
  • Packaging5G
  • Price₹14200
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberH47003
  • Product description5-Hydroxy-1,4-naphthoquinone 97%
  • Packaging1G
  • Price₹4698.05
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number420120
  • Product descriptionJuglone - CAS 481-39-0 - Calbiochem A highly selective cell-permeable, irreversible inhibitor of PPlases (peptidyl-prolyl cis/trans isomerases of the parvulin family).
  • Packaging250MG
  • Price₹6990
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberH47003
  • Product description5-Hydroxy-1,4-naphthoquinone 97%
  • Packaging5G
  • Price₹17341.65
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
ALFA India ALF-H28343-03 5-Hydroxy-1,4-naphthoquinone, 99% 1g ₹2699 2022-05-26 Buy
ALFA India ALF-H28343-06 5-Hydroxy-1,4-naphthoquinone, 99% 5g ₹13363 2022-05-26 Buy
TCI Chemicals (India) H0286 5-Hydroxy-1,4-naphthoquinone min. 96.0 % 1G ₹3700 2022-05-26 Buy
TCI Chemicals (India) H0286 5-Hydroxy-1,4-naphthoquinone min. 96.0 % 5G ₹14200 2022-05-26 Buy
Sigma-Aldrich(India) H47003 5-Hydroxy-1,4-naphthoquinone 97% 1G ₹4698.05 2022-06-14 Buy
Sigma-Aldrich(India) 420120 Juglone - CAS 481-39-0 - Calbiochem A highly selective cell-permeable, irreversible inhibitor of PPlases (peptidyl-prolyl cis/trans isomerases of the parvulin family). 250MG ₹6990 2022-06-14 Buy
Sigma-Aldrich(India) H47003 5-Hydroxy-1,4-naphthoquinone 97% 5G ₹17341.65 2022-06-14 Buy

Properties

Melting point :161-163 °C (lit.)
Boiling point :265.11°C (rough estimate)
Density :1.2346 (rough estimate)
refractive index :1.5036 (estimate)
storage temp. :Keep in dark place,Sealed in dry,Room Temperature
solubility :DMSO: 10 mg/ml; Ethanol: 10 mg/ml
form :Crystalline Powder
pka :6.59±0.20(Predicted)
color :Orange to brown
Water Solubility :SOLUBLE IN HOT WATER
Sensitive :Light Sensitive
Merck :14,5269
BRN :1909764
LogP :1.920
CAS DataBase Reference :481-39-0(CAS DataBase Reference)
NIST Chemistry Reference :1,4-Naphthalenedione, 5-hydroxy-(481-39-0)
EPA Substance Registry System :1,4-Naphthalenedione, 5-hydroxy- (481-39-0)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Juglone is a natural naphthoquinone found in the black walnut (J. nigra) and other plants in the Juglandaceae family. It has allelopathic actions, suppressing growth, photosynthesis, and respiration in plants and other organisms, although some bacteria can metabolize juglone. Juglone also irreversibly inhibits peptidyl-prolyl cis/trans isomerases of the parvulin family, including human Pin1, yeast Ess1/Ptf1, and E. coli parvulin (Ki = 55.9 nM). Juglone also blocks transcription by RNA polymerases I, II, and III (IC50s = 2-7 μM) and attenuates kidney fibrosis in rats treated with unilateral ureteral obstruction, both through Pin1-independent mechanisms.

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