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ChemicalBook > Product Catalogue >Analytical Chemistry >Standard >Pharmaceutical Impurity Reference Standards >(2-PHENOXY)METHYLSULFONYLANILINE

(2-PHENOXY)METHYLSULFONYLANILINE

(2-PHENOXY)METHYLSULFONYLANILINE Structure
  • ₹0
  • Product name: (2-PHENOXY)METHYLSULFONYLANILINE
  • CAS: 51765-51-6
  • MF: C13H13NO3S
  • MW: 263.31
  • EINECS:257-399-1
  • MDL Number:MFCD03389778
  • Synonyms:2-PHENOXYMETHANESULFOANILIDE;2-PHENOXYMETHANESULFONANILIDE;(2-PHENOXY)METHYLSULFONYLANILINE;N-(2-phenoxyphenyl)methanesulphonamide ;2-Phenoxymethanesulfonailide;Einecs 257-399-1;Nimesulide impurity-B(EP/BP);Nimesulide EP Impurity B,(N-(2-phenoxyphenyl)methanesulfonamide)
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :126℃
Boiling point :378.9±44.0 °C(Predicted)
Density :1.313
vapor pressure :0Pa at 25℃
storage temp. :Keep in dark place,Inert atmosphere,Room temperature
solubility :Chloroform (Slightly), DMSO
form :Solid
pka :8.43±0.10(Predicted)
color :White to Off-White
Water Solubility :176.1mg/L at 25℃
LogP :2.4 at 25℃

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H412 Harmful to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 3 P273, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P273 Avoid release to the environment.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330 Rinse mouth.
P501 Dispose of contents/container to..…

Description

2''-Phenoxymethanesulfonanilide is a metabolite of nimesulide (N477500), which is an antiinflammatory agent. It preferentially inhibits COX-2 over COX-1 and suppresses chemical-induced carcinogenesis in mice and rats. Nimesulide also nhibits LPS-induced TNF-alpha production.

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