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ChemicalBook > Product Catalogue >Pharmaceutical intermediates >Heterocyclic compound >Pyrimidines >Thio pyrimidine >Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate

Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate

Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate Structure
  • ₹1668 - ₹46872.25
  • Product name: Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate
  • CAS: 5909-24-0
  • MF: C8H9ClN2O2S
  • MW: 232.69
  • EINECS:227-619-0
  • MDL Number:MFCD00006085
  • Synonyms:BUTTPARK 45\03-53;ETHYL 4-CHLORO-2-METHYLTHIO-5-PYRIMIDINECARBOXYLATE;ETHYL 4-CHLORO-2-METHYLTHIOPYRIMIDINE-5-CARBOXYLATE;ETHYL 4-CHLORO-2-(METHYLSULFANYL)-5-PYRIMIDINECARBOXYLATE;2-METHYLTHIO-4-CHLORO-5-ETHOXYCARBONYLPYRIMIDINE;SIEHE AV22429;ETHYL 4-CHLORO-2-METHYLTHIO-5-PYRIMIDIN&;4-chloro-2-(methylthio)pyrimidine-5-carboxylic acid ethyl ester
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Brand

  • ALFA India
  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 5g
  • 25g
  • 100g
  • ManufacturerALFA India
  • Product numberALF-B22429-06
  • Product descriptionEthyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate, 98%
  • Packaging5g
  • Price₹1668
  • Updated2022-05-26
  • Buy
  • ManufacturerALFA India
  • Product numberALF-B22429-14
  • Product descriptionEthyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate, 98%
  • Packaging25g
  • Price₹7222
  • Updated2022-05-26
  • Buy
  • ManufacturerALFA India
  • Product numberALF-B22429-22
  • Product descriptionEthyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate, 98%
  • Packaging100g
  • Price₹45906
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberE0841
  • Product descriptionEthyl 4-Chloro-2-(methylthio)pyrimidine-5-carboxylate min. 97.0 %
  • Packaging5G
  • Price₹2800
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberE0841
  • Product descriptionEthyl 4-Chloro-2-(methylthio)pyrimidine-5-carboxylate min. 97.0 %
  • Packaging25G
  • Price₹9600
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number145963
  • Product descriptionEthyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate 98%
  • Packaging5G
  • Price₹5802.2
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number145963
  • Product descriptionEthyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate 98%
  • Packaging25G
  • Price₹16876.18
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number145963
  • Product descriptionEthyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate 98%
  • Packaging100G
  • Price₹46872.25
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
ALFA India ALF-B22429-06 Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate, 98% 5g ₹1668 2022-05-26 Buy
ALFA India ALF-B22429-14 Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate, 98% 25g ₹7222 2022-05-26 Buy
ALFA India ALF-B22429-22 Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate, 98% 100g ₹45906 2022-05-26 Buy
TCI Chemicals (India) E0841 Ethyl 4-Chloro-2-(methylthio)pyrimidine-5-carboxylate min. 97.0 % 5G ₹2800 2022-05-26 Buy
TCI Chemicals (India) E0841 Ethyl 4-Chloro-2-(methylthio)pyrimidine-5-carboxylate min. 97.0 % 25G ₹9600 2022-05-26 Buy
Sigma-Aldrich(India) 145963 Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate 98% 5G ₹5802.2 2022-06-14 Buy
Sigma-Aldrich(India) 145963 Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate 98% 25G ₹16876.18 2022-06-14 Buy
Sigma-Aldrich(India) 145963 Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate 98% 100G ₹46872.25 2022-06-14 Buy

Properties

Melting point :60-63 °C (lit.)
Boiling point :132°C/0.4mmHg(lit.)
Density :1.37±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Chloroform, Ethyl Acetate
form :Crystalline Powder
pka :-2.19±0.29(Predicted)
color :White to light yellow to beige
InChI :InChI=1S/C8H9ClN2O2S/c1-3-13-7(12)5-4-10-8(14-2)11-6(5)9/h4H,3H2,1-2H3
InChIKey :SNNHLSHDDGJVDM-UHFFFAOYSA-N
SMILES :C1(SC)=NC=C(C(OCC)=O)C(Cl)=N1
CAS DataBase Reference :5909-24-0(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate was used in the synthesis of pyrimidinopyridones, potential inhibitors of the FMS tyrosine kinase.

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