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FMoc-NH-5(ethylene glycol)-acetic acid

FMoc-NH-5(ethylene glycol)-acetic acid Structure
  • ₹0
  • Product name: FMoc-NH-5(ethylene glycol)-acetic acid
  • CAS: 635287-26-2
  • MF: C27H35NO9
  • MW: 517.57
  • EINECS:
  • MDL Number:MFCD26142982
  • Synonyms:Fmoc-PEG5-acetic acid;1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13,16,19-hexaoxa-4-azahenicosan-21-oic acid;FMoc-NH-5(ethylene glycol)-acetic acid;FMoc-NH-PEG5-CH2COOH;5,8,11,14,17-Pentaoxa-2-azanonadecanedioic acid 1-(9H-fluoren-9-ylmethyl) ester;Fmoc-NH-5(ethylene glycol)-actic acid;17-[(9-Fluorenylmethoxycarbonyl)amino]-3,6,9,12,15-pentaoxaheptadecanoic acid;{2-[2-(2-{2-[2-(9H-fluoren-9-yl-methoxycarbonylamino)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}acetic acid
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Properties

Boiling point :704.3±60.0 °C(Predicted)
Density :1.224±0.06 g/cm3(Predicted)
storage temp. :2-8°C
pka :3.39±0.10(Predicted)
form :Viscous Liquid
color :Colorless to light yellow

Safety Information

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Description

Fmoc-NH-PEG5-CH2COOH is a PEG linker containing an Fmoc-protected amine and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.