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5-Bromo-1-(2-fluoro-6-trifluoromethyl-benzyl)-6-methyl-1H-pyrimidine-2,4-dione

5-Bromo-1-(2-fluoro-6-trifluoromethyl-benzyl)-6-methyl-1H-pyrimidine-2,4-dione Structure
  • ₹0
  • Product name: 5-Bromo-1-(2-fluoro-6-trifluoromethyl-benzyl)-6-methyl-1H-pyrimidine-2,4-dione
  • CAS: 830346-48-0
  • MF: C13H9BrF4N2O2
  • MW: 381.12
  • EINECS:
  • MDL Number:MFCD12546646
  • Synonyms:5-Bromo-1-(2-fluoro-6-trifluoromethyl-benzyl)-6-methyl-1H-pyrimidine-2,4-dione;2,4(1H,3H)-Pyrimidinedione, 5-bromo-1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-6-methyl-;5-Bromo-1-[2-Fluoro-6-(trifluoromethyl)benzyl]-6-methylpyrimidine-2,4(1H,3H)-dione;5-bromo-1-{[2-fluoro-6-(trifluoromethyl)phenyl]methyl}-6-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione;Elagolix Impurity 19;5-bromo-1-(2-fluoro-6-(trifluoromethyl)benzyl)-4-hydroxy-6-methylpyrimidin-2(1H)-one;1-[2-fluoro-6-(trifluoromethyl)benzyl]-5-bromo-6-methyl-2,4(1H,3H)-pyrimidinedione;1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-5-bromo-6-methyl-2,4(1H,3H)-pyrimidinedione
Properties Safety Information Description
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :>230°C (dec.)
Density :1.684±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
solubility :Chloroform (Slightly, Heated), DMSO (Slightly), Methanol (Slightly)
pka :7.83±0.40(Predicted)
form :Solid
color :White to Off-White

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.

Description

5-Bromo-1-[2-Fluoro-6-(trifluoromethyl)benzyl]-6-methylpyrimidine-2,4(1H,3H)-dione is an intermediate in the synthesis of Elagolix, a gonadotropin-releasing hormone antagonist (GnRH) used in the treatment of endometriosis.

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Suppliers and manufacturers

career henan chemical co
5-Bromo-1-(2-fluoro-6-trifluoromethyl-benzyl)-6-methyl-1H-pyrimidine-2,4-dione
₹7.00 /1KG
5-Bromo-1-(2-fluoro-6-trifluoromethyl-benzyl)-6-methyl-1H-pyrimidine-2,4-dione CAS: 830346-48-0
Aarti Industries Limited (AIL) Laxai Life Sciences SynZeal Research Pvt Ltd
Capot Chemical Co.,Ltd.
Henan Tianfu Chemical Co.,Ltd.
Hangzhou FandaChem Co.,Ltd.
ATK CHEMICAL COMPANY LIMITED
Zhejiang ZETian Fine Chemicals Co. LTD
Jinan Carbotang Biotech Co.,Ltd.