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1H-1-Ethyl Candesartan Cilexetil

1H-1-Ethyl Candesartan Cilexetil Structure
  • ₹0
  • Product name: 1H-1-Ethyl Candesartan Cilexetil
  • CAS: 914613-35-7
  • MF: C35H38N6O6
  • MW: 638.71282
  • EINECS:
  • MDL Number:MFCD18382323
  • Synonyms:1H-1-Ethyl Candesartan Cilexetil;2-Ethoxy-1-[[2'-(1-ethyl-1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]- 1H-benzimidazole-7-carboxylic acid 1-[[(cyclohexyloxy)carbonyl]oxy]ethyl ester;2-Ethoxy-1-[[2'-(1-ethyl-1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]Methyl]-;Candesartan Cilexetil EP IMpurity E;Candesartan Cilexetil EP Impurity EQ: What is Candesartan Cilexetil EP Impurity E Q: What is the CAS Number of Candesartan Cilexetil EP Impurity E Q: What is the storage condition of Candesartan Cilexetil EP Impurity E Q: What are the applications of Candesartan Cilexetil EP Impurity E;Candesartan Cilexetil EP Impurity E (Candesartan Cilexetil N1-Ethyl Analog);1H-Benzimidazole-7-carboxylic acid, 2-ethoxy-1-[[2'-(1-ethyl-1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-, 1-[[(cyclohexyloxy)carbonyl]oxy]ethyl ester;1-cyclohexyloxycarbonyloxyethyl 2-ethoxy-3-[[4-[2-(1-ethyltetrazol-5-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylate
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Properties

Melting point :90-93°C
Boiling point :842.0±75.0 °C(Predicted)
Density :1.32
storage temp. :Refrigerator
solubility :≤30mg/ml in DMSO;30mg/ml in dimethyl formamide
form :crystalline solid
pka :3.95±0.10(Predicted)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Candesartan cilexetil is a prodrug of the potent, long-acting, and selective angiotensin II type 1 receptor (AT1) antagonist, candesartan. Clinical trials indicate a 4-16 mg/day dose of candesartan cilexetil effectively reduces diastolic blood pressure. 1H-1-ethyl Candesartan cilexetil is a process-related impurity commonly found in the bulk synthesis of candesartan cilexetil.

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