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ALOESIN

ALOESIN Structure
  • ₹0
  • Product name: ALOESIN
  • CAS: 30861-27-9
  • MF: C19H22O9
  • MW: 394.37
  • EINECS:
  • MDL Number:MFCD00869744
  • Synonyms:ALOESIN;4H-1-Benzopyran-4-one, 8-.beta.-D-glucopyranosyl-7-hydroxy-5-methyl-2-(2-oxopropyl)-;2-(2-Oxopropyl)-5-methyl-7-hydroxy-8-(β-D-glucopyranosyl)-4H-1-benzopyran-4-one;8-β-D-Glucopyranosyl-7-hydroxy-5-methyl-2-(2-oxopropyl)-4H-1-benzopyran-4-one;Aloe resin B;4H-1-Benzopyran-4-one, 8-β-D-glucopyranosyl-7-hydroxy-5-methyl-2-(2-oxopropyl)-;Aloeresin B;Aloeresin
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Boiling point :628.0±55.0 °C(Predicted)
Density :1.500±0.06 g/cm3(Predicted)
storage temp. :under inert gas (nitrogen or Argon) at 2-8°C
solubility :DMSO:122.67(Max Conc. mg/mL);311.05(Max Conc. mM)
DMF:20.0(Max Conc. mg/mL);50.71(Max Conc. mM)
Ethanol:10.0(Max Conc. mg/mL);25.36(Max Conc. mM)
PBS (pH 7.2):5.0(Max Conc. mg/mL);12.68(Max Conc. mM) pka :6.58±0.40(Predicted)
form :Pale yellow to brown powder.
color :White to off-white
LogP :0.640 (est)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H226 Flammable liquid and vapour Flammable liquids Category 3 Warning
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233 Keep container tightly closed.
P240 Ground/bond container and receiving equipment.
P241 Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242 Use only non-sparking tools.
P243 Take precautionary measures against static discharge.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P370+P378 In case of fire: Use … for extinction.
P403+P235 Store in a well-ventilated place. Keep cool.
P501 Dispose of contents/container to..…

Description

Aloesin is a C-glycosylated chromone compound found in aloe (Liliaceae) that inhibits tyrosinase (IC50 = 0.9 mM), an enzyme responsible for catalyzing the first step of the conversion of tyrosine to melanin. Derivatives of aloesin have been shown to exhibit free radical scavenging and anti-inflammatory activity. The antihyperpigmenting effects of aloesin have been explored in melanocytes.

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