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ChemicalBook > Product Catalogue >Biochemical Engineering >Polypeptide >ANGIOTENSIN III, HUMAN

ANGIOTENSIN III, HUMAN

ANGIOTENSIN III, HUMAN Structure
  • ₹0
  • Product name: ANGIOTENSIN III, HUMAN
  • CAS: 13602-53-4
  • MF: C46H66N12O9
  • MW: 931.09
  • EINECS:
  • MDL Number:MFCD00167500
  • Synonyms:ARG-VAL-TYR-ILE-HIS-PRO-PHE;ARG-VAL-TYR-ILE-HIS-PRO-PHE 2ACOH 4H2O;ARG-VAL-TYR-ILE-HIS-PRO-PHE-OH CH3COOH 4H2O;H-ARG-VAL-TYR-ILE-HIS-PRO-PHE-OH;[DES-ASP1]-ANGIOTENSIN II;DES-ASP-1-ANGIOTENSIN II ACETATE SALT;ANGIOTENSIN III ACETATE SALT;ANGIOTENSIN III
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Properties

Density :1.39±0.1 g/cm3(Predicted)
storage temp. :−20°C
solubility :H2O: 1.0 mg/mL, clear, colorless
form :Lyophilized.
pka :3.56±0.10(Predicted)
color :White to off-white

Safety Information

Symbol(GHS):
Signal word:
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Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
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Description

Angiotensin III (Ang III) is a heptapeptide agonist at the angiotensin 1 (AT1) and AT2 receptors, with a 30-fold higher affinity for AT2 compared with AT1 in HEK293 cells. Ang III is the preferred agonist for renal AT2 receptors, which are responsible for sodium excretion into the urine. Ang III induces the same level of aldosterone synthesis as Ang II but has lower vasoconstrictive activity in vivo. In the brain renin-angiotensin system, Ang III increases sympathetic nerve activity and vasopressin release and dampens the baroreflex leading to higher blood pressure.

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