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Abacavir 5’-Phosphate

Abacavir 5’-Phosphate Structure
  • ₹0
  • Product name: Abacavir 5’-Phosphate
  • CAS: 136470-77-4
  • MF: C14H19N6O4P
  • MW: 366.31
  • EINECS:
  • MDL Number:MFCD23160255
  • Synonyms:Abacavir 5’-Phosphate;(1S,4R)- 4-[2-AMino-6-(cyclopropylaMino)-9H-purin-9-yl]-2-cyclopentene-1-Methanol Dihydrogen Phosphate (Ester);(1S-cis)-Abacavir Monophosphate;[(1S,4R)-4-[2-amino-6-(cyclopropylamino)purin-9-yl]cyclopent-2-en-1-yl]methyl dihydrogen phosphate;((1S,4R)-4-(2-Amino-6-(cyclopropylamino)-9H-purin-9-yl)cyclopent-2-enyl)methyl dihydrogen phosphate;2-Cyclopentene-1-methanol, 4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-, 1-(dihydrogen phosphate), (1S,4R)-;Abacavir Impurity 13
Properties Safety Information Description
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :189-194°C (dec.)
Boiling point :749.3±70.0 °C(Predicted)
Density :1.93±0.1 g/cm3(Predicted)
storage temp. :-20°C Freezer
solubility :Methanol, Water
pka :1.91±0.10(Predicted)
form :Solid
color :White

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Abacavir 5’-Phosphate (Abacavir - In House Impurity) is a metabolite of Abacavir (A105000). Abacavir is a carbocyclic 2''-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.

More related product prices

172015-79-1 2-Amino-6-cyclopropylamino-9H-purine trans-Abacavir Hydrochloride (1R,3S)-3-[2-AMino-6-(cyclopropylaMino)-9H-purin-9-yl]cyclopentaneMethanol 2,6-Diaminopurine 1443421-69-9 Abacavir Carboxylate Abacavir Abacavir-d4 (1S,4R)-(4-Aminocyclopent-2-enyl)methanol hydrochloride Abacavir sulfate 6-aminocarbovir

Related product price

Suppliers and manufacturers

Pharmaffiliates Analytics and Synthetics P. Ltd SynZeal Research Pvt Ltd Pharma Affiliates Olympus Chemicals & Fertilizers
NewCan Biotech Limited Shanghai Haohong Scientific Co., Ltd. BOC Sciences Toronto Research Chemicals J & K SCIENTIFIC LTD. Shenzhen Polymeri Biochemical Technology Co., Ltd.