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ChemicalBook > Product Catalogue >Biochemical Engineering >Polypeptide >Azilsartan

Azilsartan

Azilsartan Structure
  • ₹9277.03 - ₹37173.05
  • Product name: Azilsartan
  • CAS: 147403-03-0
  • MF: C25H20N4O5
  • MW: 456.45
  • EINECS:808-058-6
  • MDL Number:MFCD20278186
  • Synonyms:AZILSARTAN;2-Ethoxy-1-[[2'-(4,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylic acid Azilsartan;2-Ethoxy-1-{[2′-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]methyl}-1H-benzimidazole-7-carboxylic acid;2-ethoxy -1- {[2'-(5-oxo-4,5-dihydro -1,2,4 -oxadiazol-3-yl) biphenyl-4-yl ] methyl} -1H –benzimi[d]dazole-7-carboxylic acid;2-ethoxy-1-((2'-(5-oxo-4,5-dihydro- 1,2,4-oxadiazol-3-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-benzo[d]imidazole-7-carboxylic acid;AZATMint-E;Azilsartan, ≥98% (HPLC);CS-865
Price4 Properties Safety Information Description
4 prices
Selected condition：

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 10MG
  • 50MG
  • 200MG
  • 1G
  • ManufacturerTCI Chemicals (India)
  • Product numberA2601
  • Product descriptionAzilsartan
  • Packaging200MG
  • Price₹9800
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberA2601
  • Product descriptionAzilsartan
  • Packaging1G
  • Price₹19500
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0432
  • Product descriptionAzilsartan ≥98% (HPLC)
  • Packaging50MG
  • Price₹37173.05
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0432
  • Product descriptionAzilsartan ≥98% (HPLC)
  • Packaging10MG
  • Price₹9277.03
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) A2601 Azilsartan 200MG ₹9800 2022-05-26 Buy
TCI Chemicals (India) A2601 Azilsartan 1G ₹19500 2022-05-26 Buy
Sigma-Aldrich(India) SML0432 Azilsartan ≥98% (HPLC) 50MG ₹37173.05 2022-06-14 Buy
Sigma-Aldrich(India) SML0432 Azilsartan ≥98% (HPLC) 10MG ₹9277.03 2022-06-14 Buy

Properties

Melting point :188 °C(dec.)
Density :1.42
storage temp. :Sealed in dry,2-8°C
solubility :DMSO: soluble15mg/mL (clear solution)
form :powder
pka :2.05±0.10(Predicted)
color :white to beige
InChIKey :KGSXMPPBFPAXLY-UHFFFAOYSA-N

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H413 May cause long lasting harmful effects to aquatic life Hazardous to the aquatic environment, long-term hazard Category 4
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Azilsartan is an antagonist of the angiotensin II type 1 receptor (AT1; IC50 = 0.42 μM) and the active metabolite of azilsartan medoxomil . Azilsartan is formed from azilsartan medoxomil by hydrolysis in the gastrointestinal tract and liver. Azilsartan also acts as an inverse agonist, inhibiting angiotensin II-induced accumulation of inositol-1-phosphate in COS-7 cells expressing recombinant human AT1 (IC50 = 2.6 nM). It reduces the maximal contractile response induced by angiotensin II in isolated rabbit aortic strips (pD2 = 9.9). Azilsartan (100 ng/kg, i.v.) inhibits the angiotensin II-induced pressor response in conscious normotensive rats.

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Suppliers and manufacturers

ALMELO PRIVATE LIMITED SGMR PHARMACEUTICALS PVT LTD Anant Pharmaceuticals Pvt Ltd GMFC LABS PVT LTD KARPSCHEM LABORATORIES Svak Life Sciences Lakshmi Farmachem Honour Lab Limited Smilax Laboratories Limited Vijaya Pharma And Life Science