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ChemicalBook > Product Catalogue >Biochemical Engineering >Amino Acids and Derivatives >Phenylalanine derivatives >BOC-D-3,4-Dichlorophe

BOC-D-3,4-Dichlorophe

BOC-D-3,4-Dichlorophe Structure
  • ₹10240.45
  • Product name: BOC-D-3,4-Dichlorophe
  • CAS: 114873-13-1
  • MF: C14H17Cl2NO4
  • MW: 334.2
  • EINECS:
  • MDL Number:MFCD00151887
  • Synonyms:N-ALPHA-T-BOC-3,4-DICHLORO-D-PHENYLALANINE;RARECHEM BK PT 0119;(R)-2-TERT-BUTOXYCARBONYLAMINO-3-(3,4-DICHLORO-PHENYL)-PROPIONIC ACID;(R)-N-BOC-3,4-DICHLOROPHENYLALANINE;BOC-(3,4-DI-CL)-D-PHE-OH;BOC-3,4-DICHLORO-D-PHENYLALANINE;BOC-3,4-DICHLORO-D-PHE-OH;tert-butoxycarbonyl-d-3,4-dichlorophenylalanine
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Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 1G
  • ManufacturerSigma-Aldrich(India)
  • Product number15041
  • Product descriptionBoc-D-Phe(3,4-Cl2)-OH ≥98.0% (TLC)
  • Packaging1G
  • Price₹10240.45
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 15041 Boc-D-Phe(3,4-Cl2)-OH ≥98.0% (TLC) 1G ₹10240.45 2022-06-14 Buy

Properties

Melting point :120°C
alpha :-15 º (c=1,MeOH)
Boiling point :478.1±45.0 °C(Predicted)
Density :1.3859 (rough estimate)
refractive index :1.6200 (estimate)
storage temp. :Sealed in dry,Room Temperature
pka :3.75±0.10(Predicted)
form :Solid
color :White to off-white
BRN :8428163
CAS DataBase Reference :114873-13-1(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

N-Boc-D-3,4-dichlorophenylalanine is used to prepare fluorinated β-aminoacyl 1,2,4-triazolo[4,3-a]piperazine amides as dipeptidyl peptidase IV inhibitors and antidiabetic agents. It is also used in the synthesis of N-[(R,R)-(E)-1-(3,4-dichlorobenzyl)-3- (2-oxoazepan-3-yl)carbamoyl]allyl-N-methyl-3,5-bis(trifluoromethyl)benzamide as a potent and orally active dual neurokinin NK1/NK2 receptor antagonist.

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