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ChemicalBook > Product Catalogue >Natural Products >Chalcones >BUTEIN

BUTEIN

BUTEIN Structure
  • ₹6500 - ₹23839.99
  • Product name: BUTEIN
  • CAS: 487-52-5
  • MF: C15H12O5
  • MW: 272.25
  • EINECS:207-659-5
  • MDL Number:MFCD00017300
  • Synonyms:(E)-1-(2,4-Dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)-2-propen-1-one 2',3,4,4'-Tetrahydroxychalcone;BUTEIN(P);2-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)-, (2E)-;Butein 2',3,4,4'-Tetrahydroxychalcone;2-[(E)-2-(2-aminophenyl)ethenyl]-5-methyl-quinolin-8-ol;2-[(E)-2-(2-aminophenyl)ethenyl]-5-methylquinolin-8-ol;2-[(E)-2-(2-aminophenyl)vinyl]-5-methyl-8-quinolinol;2-[(E)-2-(2-aminophenyl)vinyl]-5-methyl-quinolin-8-ol
Price4 Properties Safety Information Description
4 prices
Selected condition：

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 5MG
  • 10MG
  • 100MG
  • 1G
  • ManufacturerTCI Chemicals (India)
  • Product numberB3803
  • Product descriptionButein
  • Packaging100MG
  • Price₹6500
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberB3803
  • Product descriptionButein
  • Packaging1G
  • Price₹19500
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number72795
  • Product descriptionButein analytical standard
  • Packaging10MG
  • Price₹20643.28
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number203987
  • Product descriptionButein - CAS 487-52-5 - Calbiochem A cell-permeable, reversible, substrate competitive, plant polyphenol that acts as a specific protein tyrosine kinase inhibitor.
  • Packaging5MG
  • Price₹23839.99
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) B3803 Butein 100MG ₹6500 2022-05-26 Buy
TCI Chemicals (India) B3803 Butein 1G ₹19500 2022-05-26 Buy
Sigma-Aldrich(India) 72795 Butein analytical standard 10MG ₹20643.28 2022-06-14 Buy
Sigma-Aldrich(India) 203987 Butein - CAS 487-52-5 - Calbiochem A cell-permeable, reversible, substrate competitive, plant polyphenol that acts as a specific protein tyrosine kinase inhibitor. 5MG ₹23839.99 2022-06-14 Buy

Properties

Melting point :216°C
Boiling point :560.9±50.0 °C(Predicted)
Density :1.483±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >50 mg/mL
form :solid
pka :7.44±0.35(Predicted)
color :yellow
LogP :2.405 (est)
CAS DataBase Reference :487-52-5(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Butein is a plant polyphenol that is classified as a chalcone, due to the propenone linkage between the phenol groups. Like other polyphenols, butein is a potent antioxidant and affects the numerous pathways modulated by oxidant tone, including inflammation, cancer, and immune response. It inhibits 5-lipoxygenase, the enoyl-acyl-carrier protein reductase of P. falciparum, angiotensin-converting enzyme, and Src kinase (IC50 or Ki values of 0.01, 2.97, 0.73, and 65 μM, respectively). Butein is also a sirtuin activator, increasing trichostatin A -insensitive deacetylase activity.

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Butein
₹1.00 /1KG
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