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ChemicalBook > Product Catalogue >Biochemical Engineering >Inhibitors >GPCR & G Protein >Endothelin Receptor Antagonists >Bosentan

Bosentan

Bosentan Structure
  • ₹0
  • Product name: Bosentan
  • CAS: 147536-97-8
  • MF: C27H29N5O6S
  • MW: 551.61
  • EINECS:643-099-1
  • MDL Number:MFCD00867375
  • Synonyms:2’-bipyrimidin)-4-yl)-enoxy)( ;benzenesulfonamide,4-(1,1-dimethylethyl)-n-(6-(2-hydroxyethoxy)-5-(2-methoxyph ;ro47-0203 ;4-(tert-Butyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulf;Bosentan impurity;Bosentan (Benzenesulfonamide);bosentan , CID 104865;Bosentan, 99%, a endothelin (ET) receptor antagonist
Properties Safety Information Description
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :107-110°C
Boiling point :742.3±70.0 °C(Predicted)
Density :1.325±0.06 g/cm3(Predicted)
storage temp. :-20°C Freezer
solubility :DMSO (Slightly), Methanol (Slightly)
form :Solid
pka :4.01±0.10(Predicted)
color :White to Pale Yelloow
CAS DataBase Reference :147536-97-8(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H360 May damage fertility or the unborn child Reproductive toxicity Category 1A, 1B Danger GHS hazard pictograms
H410 Very toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
Precautionary statements:
P273 Avoid release to the environment.
P281 Use personal protective equipment as required.

Description

Bosentan is an antagonist of the endothelin receptors type A (Ki = 6.5 nM) and type B (Ki = 340 nM).

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(Trifluoromethoxy)benzene Anisole Ethoxyquin p-Anisaldehyde 4-Methoxybenzyl cyanide 4-Methoxyphenol Guaiacol p-Anisidine 2-Cyanopyrimidine 5-(2-Methoxyphenoxy)-[2,2'-bipyrimidine]-4,6(1H,5H)-dione Diethyl chloromalonate 696-45-7 4-AMINO-6-HYDROXY-2-METHYLPYRIMIDINE 2,2'-BIPYRIMIDINE 4-tert-Butylbenzenesulfonamide 5,6-Dimethoxypyrimidin-4-ylamine 150728-13-5 tert-Butylbenzene

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Suppliers and manufacturers

Alembic Pharmaceuticals Limited Cipla Ltd Glenmark Pharmaceuticals Limited HRV Global Life Sciences Venkatasai Life Sciences Rivashaa Agrotech Biopharma Pvt. Ltd. Zydus Lifesciences Ltd. Alfa Omega Pharma Mylan Laboratories Ltd GLENMARK LIFE SCIENCES LTD