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ChemicalBook > Product Catalogue >API >Nervous system drugs >Antiparkinson Drugs >Bromocriptine mesylate

Bromocriptine mesylate

Bromocriptine mesylate Structure
  • ₹9190.43 - ₹48864.05
  • Product name: Bromocriptine mesylate
  • CAS: 22260-51-1
  • MF: C33H44BrN5O8S
  • MW: 750.7
  • EINECS:244-881-1
  • MDL Number:MFCD09028065
  • Synonyms:(5'A)-2-BROMO-12'-HYDROXY-2'-(1-METHYLETHYL)-5'-(2-METHYLPROPYL)ERGOTAMAN-3',6',18-TRIONE MESYLATE;BCT;BRC;(+)-BROMOCRIPTINE MESYLATE;BROMOCRIPTINE MESYLATE;(+)-BROMOCRIPTINE METHANESULFONATE;BROMOCRIPTINE METHANESULPHONATE;BROMOCRYPTINE MESYLATE METHANESULFONATE SALT
3 prices
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Brand

  • Sigma-Aldrich(India)

Package

  • 25MG
  • 100MG
  • 250MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberB2134
  • Product description2-Bromo-α-ergocryptine methanesulfonate salt solid
  • Packaging25MG
  • Price₹9190.43
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberB2134
  • Product description2-Bromo-α-ergocryptine methanesulfonate salt solid
  • Packaging100MG
  • Price₹24735.13
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberB2134
  • Product description2-Bromo-α-ergocryptine methanesulfonate salt solid
  • Packaging250MG
  • Price₹48864.05
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) B2134 2-Bromo-α-ergocryptine methanesulfonate salt solid 25MG ₹9190.43 2022-06-14 Buy
Sigma-Aldrich(India) B2134 2-Bromo-α-ergocryptine methanesulfonate salt solid 100MG ₹24735.13 2022-06-14 Buy
Sigma-Aldrich(India) B2134 2-Bromo-α-ergocryptine methanesulfonate salt solid 250MG ₹48864.05 2022-06-14 Buy

Properties

Melting point :192-196° (dec)
alpha :D20 +95° (c = 1 in methanol-methylene chloride)
storage temp. :2-8°C
solubility :H2O: 0.8 mg/mL
form :solid
pka :4.90(at 25℃)
color :white
optical activity :[α]20/D +95°, c = 1 in methanol: methylene chloride (1:1)(lit.)
Merck :13,1400
BRN :4115238
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months
InChIKey :NOJMTMIRQRDZMT-JGYCFGIMSA-N
CAS DataBase Reference :22260-51-1(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H410 Very toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
Precautionary statements:
P273 Avoid release to the environment.

Description

Bromocriptine is a potent dopamine receptor agonist that binds the D2 receptor with highest affinity (Ki = 2.5 nM). As a result, it has found applications in combination therapy for Parkinsonism. Bromocriptine also avidly binds the serotonin receptors 5-HT1A and 5-HT1D (Ki = 12.9 and 10.7 nM, respectively), as well as α and β adrenoreceptors. It also inhibits neuronal nitric oxide synthase (IC50 = 10 μM).

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