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Calcein tetraethyl ester

Calcein tetraethyl ester Structure
  • ₹0
  • Product name: Calcein tetraethyl ester
  • CAS: 1170856-93-5
  • MF: C38H42N2O13
  • MW: 734.75
  • EINECS:
  • MDL Number:MFCD14586332
  • Synonyms:Calcein tetraethyl ester;N,N'-[(3',6'-Dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-4',5'-diyl)bis(methylene)]bis[N-(2-ethoxy-2-oxoethyl)-glycine] 1,1'-diethyl ester;Tetraethyl 2,2',2'',2'''-(((3',6'-dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-4',5'-diyl)bis(methylene))bis(azanetriyl))tetraacetate;Calceintetraethylester, >97%;Tetraethyl Fluorescein Bis(methylene)bis(azanetriyl)tetraacetate;Fluorexon tetraethyl ester;Glycine, N,N'-[(3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-4',5'-diyl)bis(methylene)]bis[N-(2-ethoxy-2-oxoethyl)-, 1,1'-diethyl ester;Tetraethyl2,2',2'',2'''-(((3',6'-dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-4',5'-diyl)bis(methylene))bis(azanetriyl))tetraacetate
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Properties

Melting point :146 - 151°C
Boiling point :825.4±65.0 °C(Predicted)
Density :1.41±0.1 g/cm3(Predicted)
storage temp. :-20°C Freezer, Under inert atmosphere
solubility :Acetonitrile (Slightly), Methanol (Slightly, Heated)
form :Solid
pka :9.20±0.20(Predicted)
color :Off-White to Light Yellow

Safety Information

Symbol(GHS):
Signal word:
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Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
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Description

Tetraethyl Fluorescein Bis(methylene)bis(azanetriyl)tetraacetate is an intermediate used in the synthesis of Calcein AM (C125400), which is a hydrophobic non-fluorescent probe that can permeate the plasma membrane and can be hydrolyzed to Calcein (sc-202090), which is an extremely fluorescent and negatively charged molecule. Calcein-AM can be used to stain living cells and in cytoplasmic Schwann cells has been observed to fluoresce bright green. Calcein-AM has been reported to be a neutral substrate for P-glycoprotein (Pgp) and multidrug resistance protein (MRP) and has been used in flow cytometry studies to analyze the function of P-gp and MRP.

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