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ChemicalBook > Product Catalogue >API >Vitamins and Minerals medicines >Vitamin C drugs >Calcium levofolinate

Calcium levofolinate

Calcium levofolinate Structure
  • ₹0
  • Product name: Calcium levofolinate
  • CAS: 80433-71-2
  • MF: C20H25CaN7O7
  • MW: 515.54
  • EINECS:801-530-2
  • MDL Number:MFCD00865527
  • Synonyms:CALCIUM LEVOFOLINATE;calcium n-(4-(((2-amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-l-glutamate;N-[4-[[(2-Amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic Acid Calcium Salt;(S)-Leucovorin calcium salt (1:1);5-Formyl-(6S)-tetrahydrofolate calcium salt;Calcium (6S)-folinate;CL 307782;L-LEUCOVORIN CALCIUM
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :240-2500C (dec)
alpha :D20 -15.1° (c = 1.82)
storage temp. :Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility :Slightly soluble in water, practically insoluble in acetone and in ethanol (96 per cent).
form :Solid
color :Off-White to Pale Beige
Stability :Hygroscopic, Light Sensitive
CAS DataBase Reference :80433-71-2(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

L-Folinic acid is a reduced folic acid and isomer of DL-folinic acid . DL-Folinic acid is a racemic mixture of D-folinic acid and L-folinic acid that has been used to prevent toxicity following therapy with high-dose methotrexate , to enhance the antitumor activity of 5-fluorouracil , and as a folate supplement. Clinical studies demonstrate that formulations containing L-folinic acid have similar efficacy and tolerability as those contianing DL-folinic acid and have been used interchangeably for modification of antitumor activity of 5-fluorouracil, while D-folinic acid is inactive.

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