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ChemicalBook > Product Catalogue >Biochemical Engineering >Inhibitors >Transmembrane Transporters >Sodium Channel Inhibitor >Camostat mesilate

Camostat mesilate

Camostat mesilate Structure
  • ₹6100 - ₹24215.53
  • Product name: Camostat mesilate
  • CAS: 59721-29-8
  • MF: C21H26N4O8S
  • MW: 494.52
  • EINECS:694-565-6
  • MDL Number:MFCD00941410
  • Synonyms:4-((4-((aminoiminomethyl)amino)benzoyl)oxy)-benzeneaceticaci2-(dimethylam ;ino)-2-oxoethylester,monomethanesulfonate ;n,n-dimethylcarbamoylmethyl4-(4-guanidinobenzoyloxy)phenylacetatemethanesul ;p-(p-guanidinobenzoyloxy)phenylaceticacid,n,n-dimethylcarbamoylmethyleste ;Camostatemesylate;CAMOSTAT MESILATE;2-(Dimethylamino)-2-oxoethyl 4-(4-guanidinobenzoyloxy)phenylacetate methanesulphonate;4-[[4-[(Aminoiminomethyl)amino]benzoyl]oxy]benzeneacetic Acid 2-(Dimethylamino)-2-oxoethyl Ester Methanesulfonate
4 prices
Selected condition:

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 10MG
  • 25MG
  • 50MG
  • 100MG
  • ManufacturerTCI Chemicals (India)
  • Product numberC2977
  • Product descriptionCamostat Mesylate
  • Packaging25MG
  • Price₹6100
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberC2977
  • Product descriptionCamostat Mesylate
  • Packaging100MG
  • Price₹10600
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0057
  • Product descriptionCamostat mesylate ≥98% (HPLC)
  • Packaging10MG
  • Price₹6375.93
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0057
  • Product descriptionCamostat mesylate ≥98% (HPLC)
  • Packaging50MG
  • Price₹24215.53
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) C2977 Camostat Mesylate 25MG ₹6100 2022-05-26 Buy
TCI Chemicals (India) C2977 Camostat Mesylate 100MG ₹10600 2022-05-26 Buy
Sigma-Aldrich(India) SML0057 Camostat mesylate ≥98% (HPLC) 10MG ₹6375.93 2022-06-14 Buy
Sigma-Aldrich(India) SML0057 Camostat mesylate ≥98% (HPLC) 50MG ₹24215.53 2022-06-14 Buy

Properties

Melting point :150-1550C
RTECS :CY1571620
storage temp. :2-8°C
solubility :H2O: ≥24mg/mL
form :powder
color :white to tan
Water Solubility :Soluble in water (100 mM), DMSO (100 mM), and ethanol (<1 mg/ml).
Merck :14,1728
Stability :Stable for 2 years? from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
CAS DataBase Reference :59721-29-8(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
H400 Very toxic to aquatic life Hazardous to the aquatic environment, acute hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
Precautionary statements:
P273 Avoid release to the environment.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Camostat is a trypsin-like protease inhibitor known to inhibit trypsin and various inflammatory proteases including plasmin, kallikrein, and thrombin. A special diet containing 1 mg/g camostat has been shown to inhibit the production of TNF-α and monocyte chemoattractant protein-1 by monocytes and to disrupt proliferation of pancreatic stellate cells in a rat model of pancreatic fibrosis. Protease regulation via camostat has also been reported to reversibly inhibit epithelial sodium channel function in human airway epithelial cell models (IC50 = 50 nM) and to enhance mucociliary clearance for up to five hours when administered by aerosol inhalation to sheep.

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