Welcome to chemicalbook!
400-158-6606
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

ChemicalBook > Product Catalogue >API >Nervous system drugs >Sedative and hypnotic >Chloral hydrate

Chloral hydrate

Chloral hydrate Structure
  • ₹2100 - ₹9900
  • Product name: Chloral hydrate
  • CAS: 302-17-0
  • MF: C2H3Cl3O2
  • MW: 165.4
  • EINECS:206-117-5
  • MDL Number:MFCD00044479
  • Synonyms:chloralex ;chloralihydras ;chloralvan ;Cohidrate;Dormal;Escre;Ethanediol,2,2,2-trichloro- ;Felsules
2 prices
Selected condition:

Brand

  • TCI Chemicals (India)

Package

  • 25G
  • 500G
  • ManufacturerTCI Chemicals (India)
  • Product numberC0073
  • Product descriptionChloral Hydrate
  • Packaging25G
  • Price₹2100
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberC0073
  • Product descriptionChloral Hydrate
  • Packaging500G
  • Price₹9900
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) C0073 Chloral Hydrate 25G ₹2100 2022-05-26 Buy
TCI Chemicals (India) C0073 Chloral Hydrate 500G ₹9900 2022-05-26 Buy

Properties

Melting point :57 °C(lit.)
Boiling point :97 °C
Density :1.43 g/mL at 20 °C
vapor pressure :19.998hPa at 25℃
refractive index :1.4603 (estimate)
Flash point :16 °C
storage temp. :0-6°C
solubility :Very soluble in water, freely soluble in ethanol (96 per cent).
pka :10(at 25℃)
form :A crystalline solid
Specific Gravity :1.91
PH :3.5-5.5 (20℃, 10%)
Water Solubility :660 g/100 mL
Merck :13,2080
BRN :1698497
Dielectric constant :5.5(15℃)
Stability :Stable, but may be air or light sensitive. Incompatible with alcohols, cyanides, iodine, strong bases, carbonates.
InChIKey :RNFNDJAIBTYOQL-UHFFFAOYSA-N
LogP :1.092 at 25℃
CAS DataBase Reference :302-17-0(CAS DataBase Reference)
IARC :2A (Vol. 63, 84, 106) 2014
NIST Chemistry Reference :Chloral hydrate(302-17-0)
EPA Substance Registry System :Chloral hydrate (302-17-0)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H330 Fatal if inhaled Acute toxicity,inhalation Category 1, 2 Danger GHS hazard pictograms P260, P271, P284, P304+P340, P310,P320, P403+P233, P405, P501
H373 May cause damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 2 Warning P260, P314, P501
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P314 Get medical advice/attention if you feel unwell.

Description

Chloral hydrate is one of the oldest sedatives used for dental sedation. It was first synthesized in 1832 by Justus von Liebig and was the first synthetic central nervous system (CNS) depressant. It was used to treat delirium tremens, insomnia, and anxiety, although it is considered an unapproved drug by the US Food and Drug Administration. Initially considered to be a safer alternative to opium, it was noted to produce rapid unconsciousness when combined with ethanol. Physical dependence can occur with chronic use.
Chloral hydrate is classified as a sedative-hypnotic and is known to induce sleep in children. It has been very popular in pediatric dentistry since the mid-1950s. Chloral hydrate is rapidly absorbed following oral administration and is converted through its first pass in the liver to trichloroethanol,its active form. Trichloroethanol is conjugated in the liver and excreted in the urine. Like other agents that are metabolized in the liver, chloral hydrate may interact with other drugs, herbs, or foods resulting in clinically significant alterations of the agents (e.g.,warfarin).

Related product price