Cytochalasin H
- ₹103216.38
- Product name: Cytochalasin H
- CAS: 53760-19-3
- MF: C30H39NO5
- MW: 493.63
- EINECS:
- MDL Number:MFCD00010539
- Synonyms:(11)cytochalasa-6(12),13,19-trien-1-one,21-(acetyloxy)-7,18-dihydroxy-16,18-di ;(7s,13e,16s,18s,19e,21r)-methyl-10-phenyl ;19-triene-1-one ;21-acetoxy-7,18-dihydroxy-16,18-dimethyl-10-phenyl-(11)cytochalasa-6(12),13, ;cytochalasinhfromphomopsissp. ;kodocytochalasin-1 ;paspalin ;paspalinpi
1 prices
Selected condition:
Brand
- Sigma-Aldrich(India)
Package
- 5MG
- ManufacturerSigma-Aldrich(India)
- Product numberC0889
- Product descriptionCytochalasin H from Phomopsis sp.
- Packaging5MG
- Price₹103216.38
- Updated2022-06-14
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Sigma-Aldrich(India) | C0889 | Cytochalasin H from Phomopsis sp. | 5MG | ₹103216.38 | 2022-06-14 | Buy |
Properties
Melting point :252-258 °C
Boiling point :587°C (rough estimate)
Density :1.1369 (rough estimate)
refractive index :1.6310 (estimate)
storage temp. :2-8°C
solubility :chloroform: 10 mg/mL, clear, colorless
pka :13.88±0.70(Predicted)
form :A lyophilisate
color :Long needles from CHCl3/Et2O
BRN :1632647
InChIKey :NAEWXXDGBKTIMN-QHDZSFFESA-N
LogP :4.758 (est)
Boiling point :587°C (rough estimate)
Density :1.1369 (rough estimate)
refractive index :1.6310 (estimate)
storage temp. :2-8°C
solubility :chloroform: 10 mg/mL, clear, colorless
pka :13.88±0.70(Predicted)
form :A lyophilisate
color :Long needles from CHCl3/Et2O
BRN :1632647
InChIKey :NAEWXXDGBKTIMN-QHDZSFFESA-N
LogP :4.758 (est)
Safety Information
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Signal word: | Danger | ||||||||||||||
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Description
The cytochalasins are cell-permeable fungal metabolites that inhibit actin polymerization. This interferes with such diverse processes as cell movement, growth, phagocytosis, degranulation, and secretion. Cytochalasin H is a potent inhibitor of actin incorporation into filaments. Like cytochalasin D , it also increases the steady-state diffusion coefficients of filaments, suggesting that it stimulates filament shortening. Cytochalasin H suppresses the production of reactive oxygen species by stimulated human neutrophils, blocks endocytosis of CD59 in lymphocytes, and shows anti-angiogenic activity both in vitro and in vivo.Related product price
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