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ChemicalBook > Product Catalogue >Analytical Chemistry >Standard >Pharmaceutical Impurity Reference Standards >D(-)-AMETHOPTERIN

D(-)-AMETHOPTERIN

D(-)-AMETHOPTERIN Structure
  • ₹0
  • Product name: D(-)-AMETHOPTERIN
  • CAS: 51865-79-3
  • MF: C20H22N8O5
  • MW: 454.44
  • EINECS:257-482-2
  • MDL Number:MFCD00006710
  • Synonyms:d-methotrexate ;n-(4-(((2,4-diamino-6-pteridinyl)methyl)methylamino)benzoyl)-d-glutamicacid ;D(-)-AMETHOPTERIN;D-(-)-AMETHOPTERIN HYDRATE;D(-)-4-AMINO-N10-METHYLPTEROYLGLUTAMIC ACID;D-(-)-N-(2,4-diamino-6-pteridinyl(dimethylamino)benzoyl)glutamic acid ;R-Methotrexate (5 mg) ((R)-2-(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)amino}benzamido)pentanedioic acid);R-Methotrexate
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :195 °C
Boiling point :561.26°C (rough estimate)
Density :1.4080 (rough estimate)
refractive index :1.6910 (estimate)
storage temp. :-20°C
solubility :Aqueous Base (Slightly, Heated, Sonicated), DMSO (Slightly), Methanol (Slightly)
form :Solid
pka :3.47±0.10(Predicted)
color :Dark Yellow to Very Dark Yellow
Stability :Hygroscopic

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H341 Suspected of causing genetic defects Germ cell mutagenicity Category 2 Warning P201,P202, P281, P308+P313, P405,P501
Precautionary statements:
P202 Do not handle until all safety precautions have been read and understood.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

R-Methotrexate is an enantiomer of Methotrexate (M260675), a folic acid antagonist. Used as a antineoplastic and antirheumatic.

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