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ChemicalBook > Product Catalogue >API >Antiallergic drugs >Antihistamines >EPINASTINE HYDROCHLORIDE

EPINASTINE HYDROCHLORIDE

EPINASTINE HYDROCHLORIDE Structure
  • ₹8000 - ₹61962.3
  • Product name: EPINASTINE HYDROCHLORIDE
  • CAS: 108929-04-0
  • MF: C16H16ClN3
  • MW: 285.77
  • EINECS:629-843-8
  • MDL Number:MFCD00933434
  • Synonyms:Elestat;3-Amino-9,13b-dihydro-1H-dibenzo[c,f]imidazo[1,5-a]azepine·hydrochloride;Asmot;Azusaleon;WAL-801Cl, 9,13b-Dihydro-1H-dibenz[cf]imidazo[1,5-a]azepine hydrochloride;1H-Dibenz[c,f]imidazo[1,5-a]azepin-3-amine, 9,13b-dihydro-, hydrochloride (1:1);WAL-801CL HCl;9,13b-Dihydro-1H-dibenz[cf]imidazo[1,5-a]azepine hydrochloride
4 prices
Selected condition:

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 10MG
  • 50MG
  • 100MG
  • 1G
  • ManufacturerTCI Chemicals (India)
  • Product numberE0799
  • Product descriptionEpinastine Hydrochloride
  • Packaging100MG
  • Price₹8000
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberE0799
  • Product descriptionEpinastine Hydrochloride
  • Packaging1G
  • Price₹19500
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberE5156
  • Product descriptionEpinastine hydrochloride ≥98% (HPLC), solid
  • Packaging10MG
  • Price₹13780.23
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberE5156
  • Product descriptionEpinastine hydrochloride ≥98% (HPLC), solid
  • Packaging50MG
  • Price₹61962.3
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) E0799 Epinastine Hydrochloride 100MG ₹8000 2022-05-26 Buy
TCI Chemicals (India) E0799 Epinastine Hydrochloride 1G ₹19500 2022-05-26 Buy
Sigma-Aldrich(India) E5156 Epinastine hydrochloride ≥98% (HPLC), solid 10MG ₹13780.23 2022-06-14 Buy
Sigma-Aldrich(India) E5156 Epinastine hydrochloride ≥98% (HPLC), solid 50MG ₹61962.3 2022-06-14 Buy

Properties

Melting point :273-275°C
storage temp. :2-8°C
solubility :H2O: soluble38mg/mL
form :solid
color :white
InChIKey :VKXSGUIOOQPGAF-UHFFFAOYSA-N

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Epinastine is a non-sedating ophthalmic antihistamine that antagonizes histamine H1 receptors (IC50 = 1.58 nM in guinea pigs) and prevents the release of pro-inflammatory mediators from mast cells and eosinophils. Although it can pass through the blood-brain barrier, the low brain distribution of epinastine is accounted for by efficient efflux transport by P-glycoproteins and poor uptake by the influx transporter. Epinastine also inhibits superoxide generation by rat neutrophils.

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