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ChemicalBook > Product Catalogue >API >Synthetic Anti-infective Drugs >Antifungal Drugs >Econazole nitrate

Econazole nitrate

Econazole nitrate Structure
  • ₹4500 - ₹48041.35
  • Product name: Econazole nitrate
  • CAS: 24169-02-6
  • MF: C18H16Cl3N3O4
  • MW: 444.7
  • EINECS:246-053-5
  • MDL Number:MFCD00058160
  • Synonyms:(RS)-1-[2,4-DICHLORO-BETA-(P-CHLOROBENZYLOXY)PHENETHYL]-IMIDAZOLE NITRATE;1-[2-[(4-chlorophenyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazolium nitrate ;ECONAZOLE NITRATE 99%-101%;ECONAZOLE NITRATE;ECONAZOLE NITRATE SALT;ECONAZOL NITRATE;1-(2,4-dichloro-beta-((p-chlorobenzyl)oxy)phenethyl)imidazole nitrate;1-[2-[(4-chlorophenyl)methoxy]-2-(2,4-dichlorophenyl)-ethyl]-1h-imidazole mononitrate
5 prices
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Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 5G
  • 25G
  • 100G
  • ManufacturerTCI Chemicals (India)
  • Product numberE0957
  • Product descriptionEconazole Nitrate
  • Packaging5G
  • Price₹4500
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberE0957
  • Product descriptionEconazole Nitrate
  • Packaging25G
  • Price₹14500
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberE4632
  • Product descriptionEconazole nitrate salt
  • Packaging5G
  • Price₹7761.53
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberE4632
  • Product descriptionEconazole nitrate salt
  • Packaging25G
  • Price₹24962.45
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberE4632
  • Product descriptionEconazole nitrate salt
  • Packaging100G
  • Price₹48041.35
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) E0957 Econazole Nitrate 5G ₹4500 2022-05-26 Buy
TCI Chemicals (India) E0957 Econazole Nitrate 25G ₹14500 2022-05-26 Buy
Sigma-Aldrich(India) E4632 Econazole nitrate salt 5G ₹7761.53 2022-06-14 Buy
Sigma-Aldrich(India) E4632 Econazole nitrate salt 25G ₹24962.45 2022-06-14 Buy
Sigma-Aldrich(India) E4632 Econazole nitrate salt 100G ₹48041.35 2022-06-14 Buy

Properties

Melting point :162°C
storage temp. :Inert atmosphere,Room Temperature
solubility :chloroform/methanol: soluble25mg/mL (choloroform:methanol (1:1))
form :powder
color :white to off-white
Water Solubility :<0.1 g/100 mL at 19 ºC
Merck :14,3502
InChIKey :DDXORDQKGIZAME-UHFFFAOYSA-N
CAS DataBase Reference :24169-02-6(CAS DataBase Reference)
EPA Substance Registry System :Econazole mononitrate (24169-02-6)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Econazole nitrate is the nitrate salt form of Econazole. It belongs to imidazole-class antifungal medication sold in various places around the world including US, Canada, Western Europe, and Asia. It is usually manufactured into cream form for sale. Econazole nitrate is mainly used for the treatment of skin infections including athlete's foot, tinea, pityriasis versicolor, ringworm, and jock itch caused by fungi such as Trichophyton rubrum, Trichophyton tonsurans and Microsporum audouini. As an imidazole-class drug, Econazole nitrate takes effects through inhibiting the biosynthesis of ergosterol, a key component of fungal cell membrane, thus disrupting the normal permeability of fungal membrane. This causes leakage of essential cellular contents of fungi, further killing them.

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