Eptifibatide
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- ₹0
- Product name: Eptifibatide
- CAS: 188627-80-7
- MF: C35H49N11O9S2
- MW: 831.96
- EINECS:641-366-7
- MDL Number:MFCD05662245
- Synonyms:MAP-LYS-GLY-ASP-TRP-PRO-CYS-NH2;INTEGRELIN;Eptifibatide;N6-(Aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl-L-lysylglycyl-L-a-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide;MPA-HAR-GLY-ASP-TRP-PRO-CYS-NH2(DISULFIDE BRIDGE, MPA1-CYS6);Intrifiban;N6-(AMinoiMinoMethyl)-N2-(3-Mercapto-1-oxopropyl)-L-lysylglycyl-L-.alpha.-aspartyl-L-tryptophyl-L-prolyl-L-cysteinaMide Cyclic (16)-Disulfide;3-Mercaptopropionyl-HoMoarg-Gly-Asp-Trp-Pro-Cys-NH2
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Properties
Density :1.60±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :DMF: 30 mg/ml,DMSO: 14 mg/ml,Ethanol: 5 mg/ml,PBS (pH 7.2): 5 mg/ml
form :A crystalline solid
pka :4.01±0.10(Predicted)
color :White to off-white
Water Solubility :Soluble to 5 mg/ml in water
InChIKey :CZKPOZZJODAYPZ-ITVGJGJRNA-N
SMILES :N12CCC[C@H]1C(=O)N[C@@H](CSSCCC(=O)N[C@@H](CCCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC1C3C=CC=CC=3NC=1)C2=O)C(N)=O |&1:4,8,17,33,41,r|
CAS DataBase Reference :188627-80-7
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :DMF: 30 mg/ml,DMSO: 14 mg/ml,Ethanol: 5 mg/ml,PBS (pH 7.2): 5 mg/ml
form :A crystalline solid
pka :4.01±0.10(Predicted)
color :White to off-white
Water Solubility :Soluble to 5 mg/ml in water
InChIKey :CZKPOZZJODAYPZ-ITVGJGJRNA-N
SMILES :N12CCC[C@H]1C(=O)N[C@@H](CSSCCC(=O)N[C@@H](CCCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC1C3C=CC=CC=3NC=1)C2=O)C(N)=O |&1:4,8,17,33,41,r|
CAS DataBase Reference :188627-80-7
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
Eptifibatide is a kind of synthetic cyclic hexapeptide consisting of 6 amino acids and 1 mercaptopropionyl residue. It is capable of binding to the platelet receptor glycoprotein (GP) IIb/IIIa of human platelets and inhibiting the platelet aggregation, thus blocking the binding of the fibrinogen, von Willebrand factor and other adhesive ligands. It is indicated for the treatment of acute coronary syndrome (ACS) and Percutaneous coronary intervention (PCI). It is able to reduce the risk of acute cardiac ischemic events in patients with unstable angina or non-ST segment-elevation myocardial infection. It is often used in combination with aspirin or clopidogrel and heparin. It can be manufactured through solution-phase peptide synthesis, and can be purified by preparative reverse-phase liquid chromatography and lyophilization.Related product price
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