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FMOC-ARG(ME,PBF)-OH

FMOC-ARG(ME,PBF)-OH Structure
  • ₹0
  • Product name: FMOC-ARG(ME,PBF)-OH
  • CAS: 1135616-49-7
  • MF: C35H42N4O7S
  • MW: 662.8
  • EINECS:
  • MDL Number:MFCD08064312
  • Synonyms:N-ALPHA-FMOC-N-OMEGA-METHYL-N-OMEGA'-(2,2,4,6,7-PENTAMETHYLDIHYDROBENZOFURAN-5-SULFONYL)-L-ARGININE;FMOC-ARG(ME,PBF)-OH;N-α-(9-Fluorenylmethoxycarbonyl)-N-ω-methyl-N-ω'-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-arginine;Fmoc-Arg(Me,Pbf);Nα-Fmoc-Nω-methyl-Nω'-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-arginine≥ 98% (HPLC);FMoc-Arg(Pbf,Me)-OH;(S,Z)-2-((((9H-Fluoren-9-yl)Methoxy)carbonyl)aMino)-5-(3-Methyl-2-((2,2,4,6,7-pentaMethyl-2,3-dihydrobenzofuran-5-yl)sulfonyl)guanidino)pentanoic acid;N5-[[[(2,3-Dihydro-2,2,4,6,7-pentamethyl-5-benzofuranyl)sulfonyl]amino](methylimino)methyl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-ornithine
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Properties

Density :1.33
storage temp. :Store at -15°C to -25°C.
pka :3.80±0.21(Predicted)

Safety Information

Symbol(GHS):
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Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
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Description

FMOC-Arg (ME, PBF)-OH is a kind of protected form of arginine. Arginine is double-protected by butyloxycarbonyl (BOC) and 2, 2, 4, 6, 7-pentamethyldihydrobenzofuran-5-sulfonyl (PBF). It is a derivative for introducing mono-methyl-arginine during Fmoc SPPS. Coupling can be carried out using any standard activation method. PBF protecting group can be removed by TFA-mediated cleavage reaction. As a kind of protected amino acid, it is an important intermediate in various fields such as peptide synthesis, asymmetric synthesis, medicinal chemistry as well as polymer chemistry.

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