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ChemicalBook > Product Catalogue >Biochemical Engineering >Plant extracts >GINSENOSIDE F2

GINSENOSIDE F2

GINSENOSIDE F2 Structure
  • ₹0
  • Product name: GINSENOSIDE F2
  • CAS: 62025-49-4
  • MF: C42H72O13
  • MW: 785.01
  • EINECS:
  • MDL Number:MFCD06410948
  • Synonyms:(20S)-3β-(β-D-Glucopyranosyloxy)-20-(β-D-glucopyranosyloxy)dammar-24-ene-12β-ol;(20S)-3β,20-Bis(β-D-glucopyranosyloxy)-5α-dammar-24-ene-12β-ol;12β-Hydroxy-5α-dammar-24-ene-3β,20-diylbis(β-D-glucopyranoside);20(S)-Ginsenoside-F2;20(S)-Ginsenoside F2 ,98%;-D-glucopyranosidederiv.;GINSENOSIDE F2;Ginsenoside F2, >=98%
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :195-200°C
Boiling point :871.5±65.0 °C(Predicted)
Density :1.30±0.1 g/cm3(Predicted)
storage temp. :Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility :DMSO (Slightly), Methanol (Slightly)
pka :12.91±0.70(Predicted)
form :Solid
color :White to Off-White
Stability :Hygroscopic

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H332 Harmful if inhaled Acute toxicity,inhalation Category 4 Warning GHS hazard pictograms P261, P271, P304+P340, P312
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Ginsenoside F2 is a ginsenoside that has been found in P. ginseng and has diverse biological activities. It increases the proliferation of human hair dermal papilla cells (HHDPCs) and HaCaT human keratinocytes when used at concentrations of 0.01, 0.1, and 1 μM. Ginsenoside F2 (0.5 and 2.5 mg/kg) induces hair growth and increases hair density following depilation in mice. It is cytotoxic to U373MG glioblastoma cells in vitro (IC50 = 50 μg/ml) and reduces tumor growth in a U373MG mouse xenograft model when administered at a dose of 35 mg/kg every other day. Ginsenoside F2 (1 mg/ear) reduces ear edema induced by phorbol 12-myristate 13-acetate (TPA; ) in mice. It is a human intestinal bacterial metabolite of ginsenoside Rb1 via the intermediate ginsenoside Rd .

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