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ChemicalBook > Product Catalogue >Organic Chemistry >Organic fluorine compound >Fluoroaniline series >Gefitinib InterMediate B

Gefitinib InterMediate B

Gefitinib InterMediate B Structure
  • ₹0
  • Product name: Gefitinib InterMediate B
  • CAS: 912556-91-3
  • MF: C18H16Cl2FN3O2
  • MW: 396.24
  • EINECS:
  • MDL Number:MFCD26383919
  • Synonyms:N-(3-chloro-4-fluorophenyl)-6-(3-chloropropoxy)-7-Methoxyquinazolin-4-aMine;Gefitinib InterMediate B;6-(3-chloropropoxy)-N-(3-chloro-4-fluorophenyl)-7-methoxyquinazolin-4-ylamine;4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-6-(3-chloropropoxy)-7-methoxy-;Gefitinib InterMediate B ISO 9001:2015 REACH;N-(3-Chloro-4-fluorophenyl)-6-(3-chloropropoxy)-7-methoxy-4-quinazolinamine
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :234-236 °C
Boiling point :523.3±50.0 °C(Predicted)
Density :1.392±0.06 g/cm3(Predicted)
storage temp. :under inert gas (nitrogen or Argon) at 2–8 °C
pka :5.40±0.30(Predicted)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.

Description

4-Chloro-6-(3-chloropropoxy)-7-methoxyquinazoline is an analogue of Gefitinib, an inhibitor of EGFR with anti-tumor activity.

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