ISOTETRANDRINE
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- Product name: ISOTETRANDRINE
- CAS: 477-57-6
- MF: C38H42N2O6
- MW: 622.76
- EINECS:
- MDL Number:MFCD00236404
- Synonyms:1-isotetrandrine ;6,6’,7,12-tetramethoxy-2,2’-dimethyl-berbama ;isosinomenina ;isosinomeninea ;o,o’-dimethylobamegine ;o,o’-dimethylstepholine ;O-METHYLBERBAMINE;BERBAMINE METHYL ETHER
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Properties
Melting point :180-182℃
Boiling point :710.5±60.0 °C(Predicted)
Density :1.172
RTECS :NX7285000
solubility :Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form :Off-white solid.
pka :7.70±0.20(Predicted)
color :White to light yellow
Boiling point :710.5±60.0 °C(Predicted)
Density :1.172
RTECS :NX7285000
solubility :Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form :Off-white solid.
pka :7.70±0.20(Predicted)
color :White to light yellow
Safety Information
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Description
Isotetrandrine is a biscoclaurine alkaloid inhibitor of G protein activation of PLA2 but not PLC or PLD. It has been suggested that isotetrandrine suppresses the receptor-mediated phospholipase A2 activation by uncoupling a GTP-binding protein from the enzyme. Isotetrandrine has been reported to inhibit collagen, thrombin, and arachidonic acid-induced platelet aggregation. Isotetrandrine has been found to inhibit arachidonic acid liberation of platelets induced by compound 48/80, antigen, GTPβS and Ca2+. Isotetrandrine is an inhibitor of AR (α1 adrenoceptor).More related product prices
Related product price
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