KIFUNENSINE
|
- ₹22039.7 - ₹34619.99
- Product name: KIFUNENSINE
- CAS: 109944-15-2
- MF: C8H12N2O6
- MW: 232.19
- EINECS:
- MDL Number:MFCD00270017
- Synonyms:KIFUNENSINE, KITASATOSPORIA KIFUNENSE;Imidazo1,2-apyridine-2,3-dione, hexahydro-6,7,8-trihydroxy-5-(hydroxymethyl)-, (5R,6R,7S,8R,8aS)-;FR 900494, Hexahydro-6R,7S,8aS-trihydroxy-5R-(hydroxymethyl)-imidazo[1,2-a] pyridine-2,3-dione;(5R,8aS)-1,5,6,7,8,8a-Hexahydro-6β,7α,8α-trihydroxy-5α-(hydroxymethyl)imidazo[1,2-a]pyridine-2,3-dione;(5R,6R,7S,8R,8aS)-Hexahydro-6,7,8-trihydroxy-5-(hydroxymethyl)-imidazo[1,2-a]pyridine-2,3-dione;[5R-(5α,6β,7α,8α,8aα)]-;Kifunensine min. 99%;FR 900494
2 prices
Selected condition：
Brand
- Sigma-Aldrich(India)
Package
- 1MG
- ManufacturerSigma-Aldrich(India)
- Product numberK1140
- Product descriptionKifunensine mannosidase inhibitor
- Packaging1MG
- Price₹22039.7
- Updated2022-06-14
- Buy
- ManufacturerSigma-Aldrich(India)
- Product number422500
- Product descriptionKifunensine, Kitasatosporia kifunense - CAS 109944-15-2 - Calbiochem A potent alkaloid inhibitor of mannosidase I.
- Packaging1MG
- Price₹34619.99
- Updated2022-06-14
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | K1140 | Kifunensine mannosidase inhibitor | 1MG | ₹22039.7 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 422500 | Kifunensine, Kitasatosporia kifunense - CAS 109944-15-2 - Calbiochem A potent alkaloid inhibitor of mannosidase I. | 1MG | ₹34619.99 | 2022-06-14 | Buy |
Properties
Melting point :>280°C
Density :1.85±0.1 g/cm3(Predicted)
storage temp. :−20°C
solubility :water, double-distilled: soluble50MM
form :White solid
pka :9.61±0.70(Predicted)
color :White
Water Solubility :Soluble to 5 mM in water with sonication
Stability :Desiccate and Store at -20°C
Density :1.85±0.1 g/cm3(Predicted)
storage temp. :−20°C
solubility :water, double-distilled: soluble50MM
form :White solid
pka :9.61±0.70(Predicted)
color :White
Water Solubility :Soluble to 5 mM in water with sonication
Stability :Desiccate and Store at -20°C
Safety Information
| Symbol(GHS): |
|
||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Warning | ||||||||||||||
| Hazard statements: |
|
||||||||||||||
| Precautionary statements: |
|
Description
Kifunensine is an immunoactive compound originally produced by Kitasatosporia kifunense, which displays competitive inhibition against immunosuppressive factor in tumor-bearing mice. Kifunensine has also been shown to be a potent inhibitor of the purified glycoprotein processing enzyme, mannosidase I (MAN1), specifically MAN1A1, MAN1A2, MAN1B1 and MAN1C1. Enzymes of this class are important factors for the biosynthesis of various types of N-linked oligosaccharide structures. Inhibition of these structures by kifunensine can interfere with cell-to-cell adhesion, targeting of lysosomal hydrolases to lysosomes, and clearance of asialoglycoproteins from the serum.Related product price
- Mupirocin
₹4300-76651.83 - VERATRIDINE
₹8603.19-132162.43 - N,N'-Bis(2-hydroxyethyl)oxamide
₹3000-93393
Suppliers and manufacturers
CLEARSYNTH LABS LTD.
TargetMol Chemicals Inc.
Zhejiang J&C Biological Technology Co.,Limited
Shanghai Acmec Biochemical Technology Co., Ltd.
Aladdin Scientific
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Guangzhou Younan Technology Co., Ltd
Shanghai Saikerui Biotechnology Co. , Ltd.
Nantong QuanYi Biotechnology Co., Ltd
Shanghai Macklin Biochemical Co.,Ltd.