MICROCYSTIN LA
- ₹0
- Product name: MICROCYSTIN LA
- CAS: 96180-79-9
- MF: C46H67N7O12
- MW: 910.064
- EINECS:
- MDL Number:MFCD32693968
- Synonyms:Microcystin-leucine-alanine;cyanoginosin-la ;toxinbe4 ;Toxin be 4 (microcystis aeruginosa);DIAQQISRBBDJIM-DRSCAGMXSA-N;Cyclo[2,3-didehydro-N-methylalanyl-D-alanyl-L-leucyl-(3S)-3-methyl-D-β-aspartyl-L-alanyl-(2S,3S,4E,6E,8S,9S)-3-amino-9-methoxy-2,6,8-trimethyl-10-phenyl-4,6-decadienoyl-D-γ-glutamyl]
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Properties
Boiling point :1237.0±65.0 °C(Predicted)
Density :1.24±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :methanol: 2 mg/mL
pka :3.03±0.70(Predicted)
form :Whitish film adhered to inside of the vial.
color :Colorless to off-white
EPA Substance Registry System :Cyclo[2,3-didehydro-N-methylalanyl-D-alanyl-L-leucyl-(3S)-3-methyl-D-.beta.-aspartyl-L-alanyl-(2S,3S,4E,6E,8S,9S)-3-amino-9-methoxy-2,6,8-trimethyl-10-phenyl-4,6-decadienoyl-D-.gamma.-glutamyl] (96180-79-9)
Density :1.24±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :methanol: 2 mg/mL
pka :3.03±0.70(Predicted)
form :Whitish film adhered to inside of the vial.
color :Colorless to off-white
EPA Substance Registry System :Cyclo[2,3-didehydro-N-methylalanyl-D-alanyl-L-leucyl-(3S)-3-methyl-D-.beta.-aspartyl-L-alanyl-(2S,3S,4E,6E,8S,9S)-3-amino-9-methoxy-2,6,8-trimethyl-10-phenyl-4,6-decadienoyl-D-.gamma.-glutamyl] (96180-79-9)
Safety Information
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Signal word: | Danger | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Description
Microcystins are hepatotoxic cyclic heptapeptide toxins produced by cyanobacteria. They are responsible for periodic poisonings of humans and livestock following consumption of freshwater in areas where the blue-green algae are endemic. The toxicity of microcystins is initiated by the inhibition of the catalytic activity of protein phosphatase (PP) 1 and PP2A. Microcystin-LA differs from the major microcystin variant LR with the substitution of alanine in place of the arginine. It inhibits both PP1C and PP2A with an IC50 value of 0.3 nM.Related product price
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