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Maleimide-PEG4-NHS Ester

Maleimide-PEG4-NHS Ester Structure
  • ₹24248
  • Product name: Maleimide-PEG4-NHS Ester
  • CAS: 756525-99-2
  • MF: C22H31N3O11
  • MW: 513.49
  • EINECS:201-258-5
  • MDL Number:MFCD11041113
  • Synonyms:alpha-MaleiMidopropionyl-oMega-succiniMidyl-4(ethylene glycol);N-[15-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-15-oxo-3,6,9,12-tetraoxapentadec-1-yl]-2,5-dihydro-2,5-dioxo-1H-pyrrole-1-propanamide;O-[N-(3-MaleiMidopropionyl)aMinoethyl]-O′-[3-(N-succiniMidyloxy)-3-oxopropyl]triethylene glycol;O-[N-(3-Maleimidopropionyl)aminoethyl]-O'-[3-(N-succinimidyloxy)-3-oxopropyl]triethylene glycol >=90% (NMR);Maleimide-NH-PEG4-CH2CH2COONHS Ester;Maleimide-PEG4-NHS Ester;2,5-dioxopyrrolidin-1-yl 19-(2,5-dioxo-2H-pyrrol-1(5H)-yl)-17-oxo-4,7,10,13-tetraoxa-16-azanonadecan-1-oate;Maleimidopropionyl-PEG4-CH2CH2COONHS Ester
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Brand

  • Sigma-Aldrich(India)

Package

  • 100MG
  • ManufacturerSigma-Aldrich(India)
  • Product number712582
  • Product descriptionO-[N-(3-Maleimidopropionyl)aminoethyl]-O′-[3-(N-succinimidyloxy)-3-oxopropyl]triethylene glycol ≥90% (NMR)
  • Packaging100MG
  • Price₹24248
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) 712582 O-[N-(3-Maleimidopropionyl)aminoethyl]-O′-[3-(N-succinimidyloxy)-3-oxopropyl]triethylene glycol ≥90% (NMR) 100MG ₹24248 2022-06-14 Buy

Properties

Density :1.36±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO
form :Solid
pka :15.01±0.46(Predicted)
color :White to off-white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Mal-amido-PEG4-NHS is a PEG linker containing a maleimide group and an NHS ester. The hydrophilic PEG spacer increases solubility in aqueous media. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.

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