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ChemicalBook > Product Catalogue >API >Antipyretic analgesics >Nonsteroidal Anti-Inflammatory Drugs (NSAIDS) >Naproxen

Naproxen

Naproxen Structure
  • ₹2118 - ₹34700
  • Product name: Naproxen
  • CAS: 22204-53-1
  • MF: C14H14O3
  • MW: 230.26
  • EINECS:244-838-7
  • MDL Number:MFCD00010500
  • Synonyms:()-2-(methoxy-2-naphthyl)-propionicacid ;()-2-(methoxy-2-naphthyl)-propionsaeure ;()-propionicaci ;(+)-2-(Methoxy-2-naphthyl)-propionic acid;(+)-2-(methoxy-2-naphthyl)-propionicacid ;(+)-2-(Methoxy-2-naphthyl)-propionsaeure;(+)-2-naphthaleneaceticaci ;(+)-6-Methoxy-alpha-methyl-2-napthaleneacetic acid
11 prices
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Brand

  • ALFA India
  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 250MG
  • 500MG
  • 1ML
  • 1g
  • 5g
  • 25g
  • 500G
  • ManufacturerALFA India
  • Product numberALF-L09855-03
  • Product description(S)-(+)-2-(6-Methoxy-2-naphthyl)propionic acid, 99%
  • Packaging1g
  • Price₹2118
  • Updated2022-05-26
  • Buy
  • ManufacturerALFA India
  • Product numberALF-L09855-06
  • Product description(S)-(+)-2-(6-Methoxy-2-naphthyl)propionic acid, 99%
  • Packaging5g
  • Price₹4867
  • Updated2022-05-26
  • Buy
  • ManufacturerALFA India
  • Product numberALF-L09855-14
  • Product description(S)-(+)-2-(6-Methoxy-2-naphthyl)propionic acid, 99%
  • Packaging25g
  • Price₹8100
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberM1021
  • Product description(S)-(+)-2-(6-Methoxy-2-naphthyl)propionic Acid min. 99.0 %
  • Packaging25G
  • Price₹8500
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberM1021
  • Product description(S)-(+)-2-(6-Methoxy-2-naphthyl)propionic Acid min. 99.0 %
  • Packaging500G
  • Price₹34700
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberN-042
  • Product descriptionNaproxen solution 1.0?mg/mL in methanol, ampule of 1?mL, certified reference material, Cerilliant?
  • Packaging1ML
  • Price₹3311.7
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number284785
  • Product description(S)-(+)-6-Methoxy-α-methyl-2-naphthaleneacetic acid 98%
  • Packaging5G
  • Price₹6733.15
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number46482
  • Product descriptionNaproxen VETRANAL?, analytical standard
  • Packaging250MG
  • Price₹8270.3
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberN8280
  • Product descriptionNaproxen meets USP testing specifications
  • Packaging5G
  • Price₹9417.75
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number284785
  • Product description(S)-(+)-6-Methoxy-α-methyl-2-naphthaleneacetic acid 98%
  • Packaging25G
  • Price₹10511.08
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1040
  • Product descriptionNaproxen Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging500MG
  • Price₹10792.53
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
ALFA India ALF-L09855-03 (S)-(+)-2-(6-Methoxy-2-naphthyl)propionic acid, 99% 1g ₹2118 2022-05-26 Buy
ALFA India ALF-L09855-06 (S)-(+)-2-(6-Methoxy-2-naphthyl)propionic acid, 99% 5g ₹4867 2022-05-26 Buy
ALFA India ALF-L09855-14 (S)-(+)-2-(6-Methoxy-2-naphthyl)propionic acid, 99% 25g ₹8100 2022-05-26 Buy
TCI Chemicals (India) M1021 (S)-(+)-2-(6-Methoxy-2-naphthyl)propionic Acid min. 99.0 % 25G ₹8500 2022-05-26 Buy
TCI Chemicals (India) M1021 (S)-(+)-2-(6-Methoxy-2-naphthyl)propionic Acid min. 99.0 % 500G ₹34700 2022-05-26 Buy
Sigma-Aldrich(India) N-042 Naproxen solution 1.0?mg/mL in methanol, ampule of 1?mL, certified reference material, Cerilliant? 1ML ₹3311.7 2022-06-14 Buy
Sigma-Aldrich(India) 284785 (S)-(+)-6-Methoxy-α-methyl-2-naphthaleneacetic acid 98% 5G ₹6733.15 2022-06-14 Buy
Sigma-Aldrich(India) 46482 Naproxen VETRANAL?, analytical standard 250MG ₹8270.3 2022-06-14 Buy
Sigma-Aldrich(India) N8280 Naproxen meets USP testing specifications 5G ₹9417.75 2022-06-14 Buy
Sigma-Aldrich(India) 284785 (S)-(+)-6-Methoxy-α-methyl-2-naphthaleneacetic acid 98% 25G ₹10511.08 2022-06-14 Buy
Sigma-Aldrich(India) PHR1040 Naproxen Pharmaceutical Secondary Standard; Certified Reference Material 500MG ₹10792.53 2022-06-14 Buy

Properties

Melting point :152-154 °C (lit.)
alpha :D +66° (in chloroform)
Boiling point :332.25°C (rough estimate)
Density :1.1450 (rough estimate)
refractive index :67.5 ° (C=1, CHCl3)
Flash point :9℃
storage temp. :2-8°C
solubility :Practically insoluble in water, soluble in ethanol (96 per cent) and in methanol.
form :powder
pka :pKa 4.28± 0.02(H2O,t =25,I=0.01) (Uncertain)
color :White to Almost white
optical activity :[α]25/D +66°, c = 1 in chloroform
Water Solubility :Insoluble in water.
Merck :14,6417
BRN :3591067
BCS Class :2
LogP :3.18
CAS DataBase Reference :22204-53-1(CAS DataBase Reference)
NIST Chemistry Reference :Naproxen(22204-53-1)
EPA Substance Registry System :2-Naphthaleneacetic acid, 6-methoxy-.alpha.-methyl-, (.alpha.S)- (22204-53-1)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
H411 Toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 2
Precautionary statements:
P202 Do not handle until all safety precautions have been read and understood.
P273 Avoid release to the environment.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

(S)-Naproxen is a non-selective COX inhibitor. The IC50 values for human recombinant COX-1 and -2 are 0.6-4.8 μM and 2.0-28.4 μM, respectively.

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