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ChemicalBook > Product Catalogue >API >Antipyretic analgesics >Nonsteroidal Anti-Inflammatory Drugs (NSAIDS) >Niflumic acid

Niflumic acid

Niflumic acid Structure
  • ₹6800 - ₹13271.45
  • Product name: Niflumic acid
  • CAS: 4394-00-7
  • MF: C13H9F3N2O2
  • MW: 282.22
  • EINECS:224-516-2
  • MDL Number:MFCD00010569
  • Synonyms:2-[3-(Trifluoromethyl)anilino]nicotinic acid, 2-(α,α,α-Trifluoro-m-toluidino)nicotinic acid;Niflumic acid,99%;LABOTEST-BB LT00451962;DONALGIN;2-(ALPHA,ALPHA,ALPHA-TRIFLUORO-M-TOLUIDINO)NICOTINIC ACID;2-(3-TRIFLUOROMETHYLANILINO)NICOTINIC ACID;2-[(3-TRIFLUOROMETHYL)PHENYL]AMINO]-3-PYRIDINECARBOXYLIC ACID;2-[(3-TRIFLUOROMETHYLPHENYL)AMINO]NICOTINIC ACID
3 prices
Selected condition:

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 10G
  • 25G
  • ManufacturerTCI Chemicals (India)
  • Product numberT2353
  • Product descriptionNiflumic Acid
  • Packaging25G
  • Price₹6800
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberN0630
  • Product descriptionNiflumic acid
  • Packaging10G
  • Price₹7133.68
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberN0630
  • Product descriptionNiflumic acid
  • Packaging25G
  • Price₹13271.45
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) T2353 Niflumic Acid 25G ₹6800 2022-05-26 Buy
Sigma-Aldrich(India) N0630 Niflumic acid 10G ₹7133.68 2022-06-14 Buy
Sigma-Aldrich(India) N0630 Niflumic acid 25G ₹13271.45 2022-06-14 Buy

Properties

Melting point :203-204 °C
Boiling point :378.0±42.0 °C(Predicted)
Density :1.3935 (estimate)
storage temp. :2-8°C
solubility :Soluble in ethanol (~50 mg/ml), acetone (50 mg/ml, Clear to Slightly Hazy, Yellow), methanol (~50 mg/ml), DMSO (56 mg/ml at 25°C), and acetonitrile (~50 mg/ml).
pka :pKa 2.26 ± 0.08;4.44± 0.03(H2O,t =25±0.1,I=0.01(NaCl))(Approximate)
form :Solid
color :Light orange to Yellow to Green
Water Solubility :19mg/L(room temperature)
Sensitive :Light Sensitive
Merck :14,6531
Stability :Stable, but may discolour in light. Incompatible with strong oxidizing agents. Hygroscopic.
InChIKey :JZFPYUNJRRFVQU-UHFFFAOYSA-N
NIST Chemistry Reference :Niflumic acid(4394-00-7)
EPA Substance Registry System :3-Pyridinecarboxylic acid, 2-[[3-(trifluoromethyl)phenyl]amino]- (4394-00-7)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H413 May cause long lasting harmful effects to aquatic life Hazardous to the aquatic environment, long-term hazard Category 4
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P273 Avoid release to the environment.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Niflumic acid is a selective inhibitor of COX-2. The IC50 values are 16 and 0.1 μM for human recombinant COX-1 and -2, respectively. The Ki values are 2 and 0.02 μM for ovine COX-1 and -2, respectively.

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