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ChemicalBook > Product Catalogue >API >Synthetic Anti-infective Drugs >Quinolones >Norfloxacin

Norfloxacin

Norfloxacin Structure
  • ₹2140 - ₹15934.4
  • Product name: Norfloxacin
  • CAS: 70458-96-7
  • MF: C16H18FN3O3
  • MW: 319.33
  • EINECS:274-614-4
  • MDL Number:MFCD00079532
  • Synonyms:Zoroxin;NORFLOXACINUM;Norfloxacin (base and/or unspecified salts);1,4-Dihydro-1-ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid;4803P;MK-0366;Norfloxacin(Nicotinate&Hcl);1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-piperazino-3-quinolinecarboxylic acid, 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid
Price8 Properties Safety Information Description
8 prices
Selected condition：

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)
  • SRL

Package

  • 100MG
  • 1G
  • 5G
  • 25G
  • 1Gms
  • 5Gms
  • ManufacturerTCI Chemicals (India)
  • Product numberN0817
  • Product descriptionNorfloxacin
  • Packaging5G
  • Price₹4700
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberN0817
  • Product descriptionNorfloxacin
  • Packaging25G
  • Price₹9500
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberN9890
  • Product descriptionNorfloxacin analytical standard, ≥98% (TLC)
  • Packaging1G
  • Price₹4091.85
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberN9890
  • Product descriptionNorfloxacin analytical standard, ≥98% (TLC)
  • Packaging5G
  • Price₹13238.98
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number33899
  • Product descriptionNorfloxacin VETRANAL?, analytical standard
  • Packaging100MG
  • Price₹14743.65
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPHR1614
  • Product descriptionNorfloxacin Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging1G
  • Price₹15934.4
  • Updated2022-06-14
  • Buy
  • ManufacturerSRL
  • Product number43000
  • Product descriptionNorfloxacin (NFX), 98%
  • Packaging5Gms
  • Price₹4990
  • Updated2022-05-26
  • Buy
  • ManufacturerSRL
  • Product number43000
  • Product descriptionNorfloxacin (NFX), 98%
  • Packaging1Gms
  • Price₹2140
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) N0817 Norfloxacin 5G ₹4700 2022-05-26 Buy
TCI Chemicals (India) N0817 Norfloxacin 25G ₹9500 2022-05-26 Buy
Sigma-Aldrich(India) N9890 Norfloxacin analytical standard, ≥98% (TLC) 1G ₹4091.85 2022-06-14 Buy
Sigma-Aldrich(India) N9890 Norfloxacin analytical standard, ≥98% (TLC) 5G ₹13238.98 2022-06-14 Buy
Sigma-Aldrich(India) 33899 Norfloxacin VETRANAL?, analytical standard 100MG ₹14743.65 2022-06-14 Buy
Sigma-Aldrich(India) PHR1614 Norfloxacin Pharmaceutical Secondary Standard; Certified Reference Material 1G ₹15934.4 2022-06-14 Buy
SRL 43000 Norfloxacin (NFX), 98% 5Gms ₹4990 2022-05-26 Buy
SRL 43000 Norfloxacin (NFX), 98% 1Gms ₹2140 2022-05-26 Buy

Properties

Melting point :220°C
Boiling point :555.8±50.0 °C(Predicted)
Density :1.2504 (estimate)
storage temp. :Keep in dark place,Sealed in dry,Room Temperature
solubility :Very slightly soluble in water, slightly soluble in acetone and in ethanol (96 per cent).
form :Crystalline Powder
pka :pKa1 6.34; pKa2 8.75(at 25℃)
color :White to yellow
Water Solubility :Soluble in acetic acid. Also soluble in acetone or cloroform. Slightly soluble in water
Merck :14,6700
Stability :Hygroscopic
InChI :InChI=1S/C16H18FN3O3/c1-2-19-9-11(16(22)23)15(21)10-7-12(17)14(8-13(10)19)20-5-3-18-4-6-20/h7-9,18H,2-6H2,1H3,(H,22,23)
InChIKey :OGJPXUAPXNRGGI-UHFFFAOYSA-N
SMILES :N1(CC)C2=C(C=C(F)C(N3CCNCC3)=C2)C(=O)C(C(O)=O)=C1
CAS DataBase Reference :70458-96-7(CAS DataBase Reference)
EPA Substance Registry System :3-Quinolinecarboxylic acid, 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)- (70458-96-7)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313 IF eye irritation persists: Get medical advice/attention.

Description

It finds it application as a fluorinated quinolone antibacterial. It is clinically used to treat urinary tract infections and prostatitis. In neutrophils from cirrhotic subjects, norfloxacin increases expression of IL-10 and heme oxygenase 1 (HO-1) and decreases expression of pro-inflammatory cytokines. Additionally, when complexed with gold(III), norfloxacin binds DNA and inhibits cellular proliferation in several cancer cell lines.

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Suppliers and manufacturers

Medi Pharma Drug House Smruthi Organics Limited Lakshmi Farmachem Ralington Pharma Alfa Omega Pharma Globela Industry Pvt Ltd Aarti Drugs Ltd (part of Aarti Group of Industries) Sreepathi Pharmaceuticals Limited Ishita Drugs And Industries Ltd Nakoda Chemicals Ltd