OTAVA-BB 7070707015
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- ₹7800 - ₹15000
- Product name: OTAVA-BB 7070707015
- CAS: 934593-90-5
- MF: C26H29NO5
- MW: 435.51
- EINECS:
- MDL Number:MFCD09907563
- Synonyms:OTAVA-BB 7070707015;CAY10585;HIF-1α inhibitor;LW6;LW8;4-Hydroxy-3-[[2-(4-tricyclo[3.3.1.13,7]dec-1-ylphenoxy)acetyl]aMino]-benzoic Acid Methyl Ester;Hypoxia inducible factor-1α inhibitor;CAY 10585;CAY-10585;CAY10585;LW6
2 prices
Selected condition：
Brand
- TCI Chemicals (India)
Package
- 25MG
- 100MG
- ManufacturerTCI Chemicals (India)
- Product numberL0334
- Product descriptionLW 6
- Packaging25MG
- Price₹7800
- Updated2022-05-26
- Buy
- ManufacturerTCI Chemicals (India)
- Product numberL0334
- Product descriptionLW 6
- Packaging100MG
- Price₹15000
- Updated2022-05-26
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| TCI Chemicals (India) | L0334 | LW 6 | 25MG | ₹7800 | 2022-05-26 | Buy |
| TCI Chemicals (India) | L0334 | LW 6 | 100MG | ₹15000 | 2022-05-26 | Buy |
Properties
Boiling point :647.4±55.0 °C(Predicted)
Density :1.295±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO:17.5(Max Conc. mg/mL);40.18(Max Conc. mM)
DMF:25.6(Max Conc. mg/mL);58.8(Max Conc. mM) pka :7.59±0.48(Predicted)
form :powder to crystal
color :White to Light yellow to Light orange
Density :1.295±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO:17.5(Max Conc. mg/mL);40.18(Max Conc. mM)
DMF:25.6(Max Conc. mg/mL);58.8(Max Conc. mM) pka :7.59±0.48(Predicted)
form :powder to crystal
color :White to Light yellow to Light orange
Safety Information
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Description
Hypoxia Inducible Factor-1α Inhibitor is a novel small molecule which inhibits HIF by reducing HIF-1α accumulation and gene transcriptional activity. In a gene reporter assay using human AGS and Hep3B cell lines, hypoxia inducible factor-1α Inhibitor prevented HIF-1 transcriptional activity with IC50 values of 2.6 and 0.7 μM, respectively. Hypoxia inducible factor-1α inhibitor blocks HIF-1α accumulation in Hep3B cells in a concentration and time-dependent manner, with complete inhibition at a concentration of 30 μM within 12 hours. Hypoxia inducible factor-1α inhibitor also significantly suppresses transcription of the HIF-1 target genes VEGF and erythropoietin at 10 μM.More related product prices
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