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ChemicalBook > Product Catalogue >API >Circulatory system drugs >Antihypertensive drugs >Osthole

Osthole

Osthole Structure
  • ₹6795 - ₹43209
  • Product name: Osthole
  • CAS: 484-12-8
  • MF: C15H16O3
  • MW: 244.29
  • EINECS:1532714-185-1
  • MDL Number:MFCD00076049
  • Synonyms:Cnidiumfruitextract;Osthol/Osthole;Cnidium;OSTHOLE(P);Epiandrosterone, 99%, HPLC;Cnidiumlactone,Osthol;7-Methoxy-8-prenyl-2H-1-benzopyran-2-one;7-Methoxy-8-(3-methyl-2-buten-1-yl)-2H-chromen-2-one
11 prices
Selected condition:

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)
  • ottokemi

Package

  • 10MG
  • 25MG
  • 50MG
  • 250MG
  • 1gm
  • 1G
  • 5G
  • 5gm
  • ManufacturerTCI Chemicals (India)
  • Product numberO0426
  • Product descriptionOsthole min. 98.0 %
  • Packaging250MG
  • Price₹6800
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberO0426
  • Product descriptionOsthole min. 98.0 %
  • Packaging1G
  • Price₹9800
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberO0426
  • Product descriptionOsthole min. 98.0 %
  • Packaging5G
  • Price₹16100
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberO9265
  • Product descriptionOsthole
  • Packaging10MG
  • Price₹14018.38
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product number78889
  • Product descriptionOsthole analytical standard
  • Packaging25MG
  • Price₹26802.7
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberO9265
  • Product descriptionOsthole
  • Packaging50MG
  • Price₹32345.1
  • Updated2022-06-14
  • Buy
  • Manufacturerottokemi
  • Product number O 1350
  • Product descriptionOsthole 95%+
  • Packaging50mg
  • Price₹43209
  • Updated2022-05-26
  • Buy
  • Manufacturerottokemi
  • Product number O 1352
  • Product descriptionOsthole, >98%(GC)
  • Packaging5gm
  • Price₹16002
  • Updated2022-05-26
  • Buy
  • Manufacturerottokemi
  • Product number O 1350
  • Product descriptionOsthole 95%+
  • Packaging10mg
  • Price₹12609
  • Updated2022-05-26
  • Buy
  • Manufacturerottokemi
  • Product number O 1352
  • Product descriptionOsthole, >98%(GC)
  • Packaging1gm
  • Price₹9792
  • Updated2022-05-26
  • Buy
  • Manufacturerottokemi
  • Product number O 1352
  • Product descriptionOsthole, >98%(GC)
  • Packaging250mg
  • Price₹6795
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) O0426 Osthole min. 98.0 % 250MG ₹6800 2022-05-26 Buy
TCI Chemicals (India) O0426 Osthole min. 98.0 % 1G ₹9800 2022-05-26 Buy
TCI Chemicals (India) O0426 Osthole min. 98.0 % 5G ₹16100 2022-05-26 Buy
Sigma-Aldrich(India) O9265 Osthole 10MG ₹14018.38 2022-06-14 Buy
Sigma-Aldrich(India) 78889 Osthole analytical standard 25MG ₹26802.7 2022-06-14 Buy
Sigma-Aldrich(India) O9265 Osthole 50MG ₹32345.1 2022-06-14 Buy
ottokemi O 1350 Osthole 95%+ 50mg ₹43209 2022-05-26 Buy
ottokemi O 1352 Osthole, >98%(GC) 5gm ₹16002 2022-05-26 Buy
ottokemi O 1350 Osthole 95%+ 10mg ₹12609 2022-05-26 Buy
ottokemi O 1352 Osthole, >98%(GC) 1gm ₹9792 2022-05-26 Buy
ottokemi O 1352 Osthole, >98%(GC) 250mg ₹6795 2022-05-26 Buy

Properties

Melting point :83-84°C
Boiling point :347.2°C (rough estimate)
Density :1.1263 (rough estimate)
refractive index :1.5570 (estimate)
storage temp. :Sealed in dry,2-8°C
solubility :methanol: soluble10mg/mL, clear, colorless
form :powder
color :white
Odor :at 100.00 %. dry musty herbal
Odor Type :dry
Water Solubility :12mg/L(25 ºC)
λmax :322nm(MeOH)(lit.)
Merck :14,6895
InChIKey :MBRLOUHOWLUMFF-UHFFFAOYSA-N
LogP :3.686 (est)
CAS DataBase Reference :484-12-8(CAS DataBase Reference)
NIST Chemistry Reference :Osthole(484-12-8)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P501 Dispose of contents/container to..…

Description

Osthole is a natural coumarin that was first isolated from several medicinal plants, including C. monnieri and A. pubescens. It is reported to induce a nonspecific elevation of cAMP and cGMP levels through its ability to inhibit phosphodiesterases, which leads to a modulation of calcium channel signaling and vasorelaxant effects. Osthole exhibits immunomodulatory, antioxidative, and anti-inflammatory properties, by regulating the expression of TNF-α, NF-κB, TGF-β, cyclooxygenases, leukotrienes, nitric oxide, ERK, and JNK. It also demonstrates antifibrotic effects in both hepatic and myocardial tissues and has been suggested to be a natural activator of defective delta F508-cystic fibrosis transmembrane conductance regulator chloride channel gating.

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