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ChemicalBook > Product Catalogue >Natural Products >Phenols >PRUNASIN

PRUNASIN

PRUNASIN Structure
  • ₹42304.1
  • Product name: PRUNASIN
  • CAS: 99-18-3
  • MF: C14H17NO6
  • MW: 295.29
  • EINECS:202-738-0
  • MDL Number:MFCD00049232
  • Synonyms:D-Mandelonitrile β-D-glucoside;(R)-α-(β-D-Glucopyranosyloxy)benzeneacetonitrile;(αR)-α-(β-D-Glucopyranosyloxy)-α-phenylacetonitrile;[(αR)-α-Cyanobenzyl]β-D-glucopyranoside;Prunacin;(2R)-2-phenyl-2-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyacetonitrile;(2R)-2-phenyl-2-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-ethanenitrile;(2R)-2-phenyl-2-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-methylol-tetrahydropyran-2-yl]oxy-acetonitrile
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Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 1MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberSMB00173
  • Product descriptionPrunasin ≥90% (LC/MS-ELSD)
  • Packaging1MG
  • Price₹42304.1
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) SMB00173 Prunasin ≥90% (LC/MS-ELSD) 1MG ₹42304.1 2022-06-14 Buy

Properties

Melting point :138-148°C
Boiling point :527.0±50.0 °C(Predicted)
Density :1.45±0.1 g/cm3(Predicted)
storage temp. :Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility :Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form :Powder
pka :12.71±0.70(Predicted)
color :White to off-white
Stability :Hygroscopic

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H360 May damage fertility or the unborn child Reproductive toxicity Category 1A, 1B Danger GHS hazard pictograms
Precautionary statements:
P201 Obtain special instructions before use.

Description

(R)-Prunasin is a cyanogenic glucoside that is the precursor to amygdalin, a bitter component found in species of the genera Prunus and Olinia. It can be degraded to hydrogen cyanide, glucose, and benzaldehyde by the action of prunasin hydrolase and mandelonitrile lyase and possesses inhibitory effects on plant growth. (R)-Prunasin reportedly inhibits rat DNA polymerase β, which performs base excision repair required for DNA maintenance and replication, with an IC50 value of 98 μM.

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