Pachymic acid
![]() |
- ₹0
- Product name: Pachymic acid
- CAS: 29070-92-6
- MF: C33H52O5
- MW: 528.76
- EINECS:
- MDL Number:MFCD00238657
- Synonyms:3-ACETYLTUMULOSIC ACID;PACHYMIC ACID;(3b,16a)-3-(Acetyloxy)-16-hydroxy-24-methylenelanost-8-en-21-oic acid;24-methylene-,(3β,16α)-;3-O-Acetyltumulosic acid;Lanost-8-en-21-oic acid, 3-(acetyloxy)-16-hydroxy-;3β-Acetyloxy-16α-hydroxy-24-methylenelanost-8-en-21-oic acid;Ccris 7792
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|
Properties
Melting point :300 °C(Solv: methanol (67-56-1); acetone (67-64-1))
Boiling point :612.2±55.0 °C(Predicted)
Density :1.10±0.1 g/cm3(Predicted)
storage temp. :Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility :Methanol (Slightly), Pyridine (Slightly)
form :Solid
pka :4.65±0.10(Predicted)
color :White to Off-White
Stability :Hygroscopic
Boiling point :612.2±55.0 °C(Predicted)
Density :1.10±0.1 g/cm3(Predicted)
storage temp. :Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility :Methanol (Slightly), Pyridine (Slightly)
form :Solid
pka :4.65±0.10(Predicted)
color :White to Off-White
Stability :Hygroscopic
Safety Information
Symbol(GHS): | ||||||||
---|---|---|---|---|---|---|---|---|
Signal word: | ||||||||
Hazard statements: |
|
|||||||
Precautionary statements: |
|
Description
Pachymic acid (PA) is a lanostane-type triterpenoid from Poriacocos, which is an important component in traditional Chinese medicine. Previous studies have shown that PA possesses anti-emetic, anti-inflammatory and anticancer properties. It has been demonstrated that PA is able to inhibit the proliferation and invasion of pancreatic cancer cells by decreasing MMP-7 expression. PA was able to activate reactive oxygen species (ROS)-dependent JUN N-terminal kinase mitochondrial and endoplasmic reticulum stress pathways following cell cycle arrest at G2/M phase and cell apoptosis occurred in lung cancer cells. PA reduced proliferation and induced apoptosis through inactivation of AKT signaling and downregulation of AKT downstream protein expression in prostate cancer cells. Another study demonstrated that PA is able to stimulate glucose uptake by enhancing the expression and translocation of glucose transporter type 4. However, the therapeutic effects and potential mechanisms of PA on gastric cancer are poorly understood and therefore remain to be evaluated.More related product prices
CHLOROPHOSPHONAZO III Glycine Folic acid Citric acid ACETIC ACID CITRONELLIC ACIDRelated product price
- CHLOROPHOSPHONAZO III
₹4180-73610 - Glycine
₹280-116823.4 - Folic acid
₹260-31316.73
Suppliers and manufacturers
CLEARSYNTH LABS LTD.
Henan Tianfu Chemical Co.,Ltd.
Chengdu Greenpure Biopharma CO.,Ltd
Chengdu GLP biotechnology Co Ltd
Chengdu Biopurify Phytochemicals Ltd.
Xi'an Kono chem co., Ltd.,
Shaanxi Pioneer Biotech Co., Ltd .
Shanghai Longyu Biotechnology Co., Ltd.